What is trimetazidine used for?

What is trimetazidine used for?

Trimetazidine belongs to the class of medications called fatty acid oxidation inhibitors. It is used to prevent and treat the symptoms of angina (chest pain). Angina is caused by lack of blood supply and oxygen to your heart.

Is trimetazidine bad for the kidney?

Trimetazidine is contraindicated in patients with severe renal impairment. For patients with moderate renal impairment and the elderly, the dose should be reduced.

What is the effect of trimetazidine?

Trimetazidine has a significant side effects profile, with the most common adverse reactions being nausea, vomiting, fatigue, dizziness, and myalgia. The drug can induce or increase parkinsonian symptoms: extrapyramidal rigidity, bradykinesia, and tremor.

How long should you take trimetazidine?

In conclusion, treatment with trimetazidine added to the usual treatment for up to 18 months was well tolerated and induced functional improvement in patients with ischaemic dilated cardiomyopathy. Trimetazidine treatment was associated with a significant improvement of LV function and the remodelling process.

Is trimetazidine safe?

Trimetazidine has been generally very well tolerated in clinical trials and usually only isolated cases of adverse events (ADRs—adverse drug reactions) were observed during trimetazidine treatment (mainly gastrointestinal disturbances, vomiting, nausea) [61].

Is trimetazidine good for the heart?

Previous studies have shown that trimetazidine improves cardiac function by improving hemodynamics; however, the protective effect of trimetazidine on ischemic heart failure is not entirely due to its effects on the hemodynamic system.

Can I stop taking trimetazidine?

Trimetazidine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.

Are there any side effects to taking trimetazidine?

In addition, the CHMP noted that trimetazidine is often used to treat these conditions in older patients for longer and at higher doses than recommended, increasing the risk of side effects such as falls, which undermines the use of trimetazidine for these conditions.

What kind of drug is trimetazidine used for?

Trimetazidine is a drug for angina pectoris sold under the brand name Vastarel MR. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France).

When to take trimetazidine for tinnitus and dizziness?

Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for tinnitus and dizziness. It is taken twice a day.

How is trimetazidine used in the treatment of angina?

Controlled studies in angina patients have shown that trimetazidine increases coronary flow reserve, thereby delaying the onset of ischemia associated with exercise, limits rapid swings in blood pressure without any significant variations in heart rate, significantly decreases the frequency of angina attacks,…

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