What is Upshaw Schulman syndrome?
Hereditary thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) is a rare disorder characterized by thrombocytopenia as a result of platelet consumption, microangiopathic hemolytic anemia, occlusion of the microvasculature with von Willebrand factor-platelet-thrombic and ischemic end organ damage.
What is thrombotic thrombocytopenia purpura?
Thrombotic thrombocytopenic purpura is a rare disorder that causes blood clots (thrombi) to form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and restrict blood flow to organs such as the brain, kidneys, and heart.
What causes thrombotic thrombocytopenia?
Causes. A lack of activity in the ADAMTS13 enzyme (a type of protein in the blood) causes thrombotic thrombocytopenic purpura (TTP). The ADAMTS13 gene controls the enzyme, which is involved in blood clotting. Not having enough enzyme activity causes overactive blood clotting.
What is the difference between primary and secondary thrombocytopenia?
—Same characteristics as primary ITP, but associated with several underlying conditions, which may be difficult to detect. Like primary immune thrombocytopenia (ITP), secondary ITP is characterized by reduced platelet production, or increased platelet destruction.
What is the ICD 10 cm code for thrombocytopenia?
Thrombocytopenia, unspecified Acquired thrombocytopenia; Thrombocytopenia (low blood platelets); Thrombocytopenic disorder ICD-10-CM Diagnosis Code D69.42 [convert to ICD-9-CM] Congenital and hereditary thrombocytopenia purpura
What is the diagnosis code for thrombocytopenic purpura?
Acquired thrombocytopenia; Thrombocytopenia (low blood platelets); Thrombocytopenic disorder ICD-10-CM Diagnosis Code D69.2 [convert to ICD-9-CM]
What is the ICD 10 code for thrombotic microangiopathy?
Thrombotic microangiopathy. M31.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2019 edition of ICD-10-CM M31.1 became effective on October 1, 2018. This is the American ICD-10-CM version of M31.1 – other international versions of ICD-10 M31.1 may differ.
What is the definition of immune thrombocytopenia ( ITP )?
Immune thrombocytopenic purpura. An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. Itp is a diagnosis of exclusion and is heterogeneous in origin. Bleeding or bruising tendency due to low platelet level Thrombocytopenia occurring in the absence of toxic exposure…