Is metronidazole gel safe in first trimester?
We found no association between metronidazole treatment during the first or later trimesters of pregnancy and preterm birth, low birth weight, or congenital anomalies.
Does metronidazole gel make you discharge?
Frequently asked questions about metronidazole (vaginal) A common side effect from metronidazole (vaginal) is a thick, white vaginal discharge with or without an odor which usually goes away soon after completing a full course of treatment.
Does metronidazole gel cause miscarriage?
Can metronidazole increase the chance for miscarriage? Miscarriage can occur in any pregnancy. It is unlikely that metronidazole would greatly increase the chance of a miscarriage.
Can I use Metrogel while pregnant?
Because animal reproduction studies are not always predictive of human response, METROGEL® (metronidazole gel), 1% should be used during pregnancy only if clearly needed.
Can metronidazole cause miscarriage in early pregnancy?
In a nested case control study of more than 95,000 pregnant women in Quebec, Canada, researchers from the Universite de Montreal found that the use macrolides (excluding erythromycin), quinolones, tetracyclines, sulfonamides, and metronidazole was associated with increased risk of miscarriage in early pregnancy, with …
Can metronidazole destroy pregnancy?
Many classes of common antibiotics, such as macrolides, quinolones, tetracyclines, sulfonamides and metronidazole, were associated with an increased risk of miscarriage in early pregnancy, according to a new study.
Why do I still have discharge after taking metronidazole?
Metronidazole vaginal will not treat a vaginal yeast infection. You may even develop a new vaginal yeast infection after using this medicine. Watch for symptoms such as itching or discharge during or after treatment with metronidazole vaginal.
Can metronidazole affect pregnancy test?
Most medicines, over-the-counter and prescription, including birth control pills and antibiotics, should not affect the results of a home pregnancy test. Only medicines that have the pregnancy hormone hCG in them can give a false positive test result.
What are the effects of metronidazole in early pregnancy?
Do not take tinidazole during the first 3 months of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. A medicine similar to tinidazole has caused cancer in laboratory animals. It is not known if tinidazole would have the same effect in animals, or in humans.
How do you treat BV in first trimester?
BV is treated with antibiotics. Antibiotics are medicines that kill infections caused by bacteria. The antibiotic may be oral (taken by mouth) or a cream or gel that you put into your vagina. Treatment with antibiotics for BV is safe for your baby during pregnancy, and it may help reduce your risk for STIs.
How do you know when metronidazole gel is working?
For some of the infections that metronidazole is used for, you may only begin to notice an improvement after a week. When using the cream or gel to treat rosacea, you may have to wait a few weeks before you see any improvement. It’s very important that you keep taking metronidazole until the course is finished.
How long does metronidazole gel stay in your system?
by Drugs.com The elimination half life of metronidazole is approximately 8 hours. It takes 5.5 x elimination half life for a medicine to be completely cleared from the body. Therefore it will take about 44 hours (5.5 x 8 hrs) for it to be cleared from your system.
How much Metronidazole is in Metrogel vaginal gel?
The gel is formulated at pH 4.0. The gel also contains carbomer 934P, edetate disodium, methylparaben, propylparaben, propylene glycol, and sodium hydroxide. Each applicator full of 5 grams of vaginal gel contains approximately 37.5 mg of metronidazole.
What is the NDC number for metronidazole 0.75%?
Metronidazole Vaginal Gel, 0.75% is supplied in a 70 g tube and packaged with 5 vaginal applicators. The NDC number for the 70 g tube is 68682-455-70. Store at controlled room temperature 15° to 30°C (59° to 86°F).
When is the best time to take metronidazole?
DOSAGE AND ADMINISTRATION. The recommended dose is one applicator full of Metronidazole Vaginal Gel (approximately 5 grams containing approximately 37.5 mg of metronidazole) intravaginally once or twice a day for 5 days. For once-a-day dosing, Metronidazole Vaginal Gel should be administered at bedtime.
Is it safe to give metronidazole to pregnant women?
There are no adequate and well-controlled studies with the use of metronidazole in pregnant women. Metronidazole crosses the placental barrier and enters the fetal circulation rapidly. No fetotoxicity was observed after oral administration of metronidazole in rats or mice at 200 and 20 times, respectively, the expected clinical dose.