Can thiamine deficiency be genetic?
A rare condition known as genetic beriberi is inherited (passed down through families) and is associated with an inability to absorb thiamine from foods.
Who is more prone to thiamine deficiency?
Risk factors for thiamine deficiency 42 Most other cases of thiamine deficiency occur among alcoholics,28 postoperative bariatric surgery patients,55 or patients with advanced HIV infection/AIDS,56, 57 who tend to have low thiamine intakes or absorption and impaired thiamine utilization.
What are the three most common reasons for thiamine deficiency?
| Thiamine deficiency | |
|---|---|
| Types | Wet, dry, gastrointestinal |
| Causes | Not enough thiamine |
| Risk factors | Diet of mostly white rice; alcoholism, dialysis, chronic diarrhea, diuretics |
| Prevention | Food fortification |
Is vitamin B-1 deficiency hereditary?
Excess alcohol makes it harder for the body to absorb and store vitamin B1. In rare cases, beriberi can be genetic. This condition is passed down through families. People with this condition lose the ability to absorb thiamine from foods.
How do you fix thiamine deficiency?
The only treatment for thiamine deficiency is thiamine supplementation and changes to any underlying dietary habits that may have caused the deficiency. Thiamine supplementation can be given orally or by injection, depending on the type and cause of thiamine deficiency you have.
Can you reverse thiamine deficiency?
“It simply isn’t possible to provide enough thiamine via the oral route, or to provide it fast enough to correct an existing brain thiamine deficiency. Ultimately IV administration of high doses is the only way to reliably accomplish this.”
What happens if you have a thiamine deficiency?
A thiamine deficiency can cause a disorder called beriberi, which has been seen in certain undernourished populations for thousands of years. Beriberi can lead to muscle wasting and severe cardiovascular problems, including an enlarged heart. Thiamine deficiency is not very common in Western, developed nations.
When does thiamine deficiency cause abdominal pain in children?
Gastrointestinal beriberi causes abdominal pain. Gastrointestinal beriberi is characterized by: Infantile beriberi usually occurs between two and six months of age in children whose mothers have inadequate thiamine intake. It may present as either wet or dry beriberi.
What foods can you eat if you have a thiamine deficiency?
Thiamine, also known as vitamin B1, is one of eight essential B vitamins that has many important functions throughout the body. ). Since the human body is unable to produce thiamine, it must be consumed through various thiamine-rich foods, such as meat, nuts and whole grains. Thiamine deficiency is fairly uncommon in developed countries.
What are the rare genetic diseases of thiamine transport?
Genetic diseases of thiamine transport are rare but serious. Thiamine responsive megaloblastic anemia syndrome (TRMA) with diabetes mellitus and sensorineural deafness is an autosomal recessive disorder caused by mutations in the gene SLC19A2, a high affinity thiamine transporter.