What are the symptoms of sitosterolemia?

What are the symptoms of sitosterolemia?

Large xanthomas can cause pain, difficulty with movement, and cosmetic problems. Joint stiffness and pain resulting from plant sterol deposits may also occur in individuals with sitosterolemia. Less often, affected individuals have blood abnormalities.

What is the best source of beta sitosterol?

Among some of the foods especially rich in beta-sitosterol are:

• Avocados: 95 mg per cup.
• Pistachio nuts (raw): 71 mg per cup.
• Almonds (raw): 46 mg per cup.
• Fava beans (fresh): 41 mg per cup.
• Soybean oil: 39 mg per tablespoon.
• Hazelnuts: 34 mg per cup.
• Walnuts: 33 mg per cup.
• Pink lentils: 27 mg per cup10.

What do plant sterols do for you?

Plant sterols are a group of plant substances that resemble cholesterol. They might help reduce cholesterol levels by limiting the amount of cholesterol that is able to enter the body. Some plant sterols might also reduce how much cholesterol is made in the body.

What is Phytosterolemia?

Abstract. Sitosterolemia or phytosterolemia is a rare autosomal recessive hereditary lipid storage disorder. It is caused by homozygous or compound heterozygous mutations in one of the two ABCG5 and ABCG8 genes encoding the intestinal and hepatic heterodimer ABCG5 (sterolin 1)/ABCG8 (sterolin 2) efflux transporters.

Do plant sterols cause muscle pain?

These can include memory loss, muscle pain or damage, weakness, and nausea. Sterols, on the other hand, are not known to cause side effects when used short-term.

What is CTX disease?

Overview. Cerebrotendinous xanthomatosis (CTX) is a rare condition that affects the body’s ability to metabolize fats known as cholesterols. Patients with CTX are unable to break down different forms of cholesterol, which build up in certain areas of the body.

What are the side effects of beta-sitosterol?

When taken by mouth: Beta-sitosterol is LIKELY SAFE for most people when taken by mouth. It can cause some mild side effects, such as nausea, indigestion, gas, diarrhea, or constipation. Less commonly, beta-sitosterol has been linked to reports of erectile dysfunction (ED), loss of interest in sex, and worsened acne.

Is beta-sitosterol the same as saw palmetto?

Saw palmetto is a plant, whereas beta sitosterol is a chemical that occurs in many plant foods. Saw palmetto is a plant, and beta sitosterol is a chemical that naturally occurs in many plant foods, including saw palmetto. Both may have biological effects in humans, but the long term effects of both are not well known.

What is homozygous familial sitosterolemia?

Homozygous sitosterolemia is an inherited disorder of sterol metabolism in which an excess of many plant sterols, including sitosterol, is absorbed and not enough excreted. (Sterols are substances used to form hormones, vitamins and membranes found in animal and plant lipids.).

Is CTX curable?

There is no cure for CTX, however, if the condition is treated early, its progression can be slowed or stopped. The first treatment generally prescribed is chenodeoxycholic acid (CDCA) replacement therapy, which works to normalize the body’s ability to break down cholesterol.