What does sibutramine do to the body?
Sibutramine is an anti-obesity drug that produces short-term and modest body weight reductions mainly due to its appetite-suppressing effect. Despite being a useful drug in obesity treatment, awareness about the loss of effectiveness and detrimental side effects of sibutramine has recently emerged.
How long can I take sibutramine?
Your blood pressure and pulse will need to be checked often. Visit your doctor regularly. Sibutramine should not be taken for longer than 2 years.
Does sibutramine work for weight loss?
At 1 year, adults receiving sibutramine, 10 to 15 mg/d, lost an average of 4.5 kg (9.8 pounds) more than adults receiving placebo. Adults taking sibutramine for 1 year are 19% to 34% more likely to achieve 5% weight loss and 12% to 31% more likely to achieve 10% weight loss than those taking placebo.
How long does it take for sibutramine to leave your system?
Sibutramine
| Clinical data | |
|---|---|
| Protein binding | 97%, (94% for its desmethyl metabolites, M1 & M2) |
| Metabolism | Hepatic (CYP3A4-mediated) |
| Elimination half-life | 1 hour (sibutramine), 14 hours (M1) & 16 hours (M2) |
| Excretion | Urine (77%), feces (8%) |
How safe is sibutramine?
In summary, the data from this 52-week study indicate that, compared with placebo, sibutramine 20 mg is safe, well tolerated, and produces statistically and clinically significant body weight loss in obese patients whose hypertension is well controlled with an ACE inhibitor, with or without concomitant thiazide …
Why is sibutramine banned?
Sibutramine was a prescription-only weight loss medicine in Singapore but has been banned since 2010 due to an increased risk of heart attack and strokes. Other serious adverse effects reported in the past by consumers who took products adulterated with sibutramine include insomnia and hallucinations.
Does sibutramine affect fertility?
The comprehensive pharmacological reactivity assays of epididymal cauda duct and ventral prostate, detailed described and validated, showed that a possible epididymal NE depletion exerted by sibutramine is associated with decreases in sperm transit time, quantity and quality, leading to reduced fertility.
What type of drug is sibutramine?
Sibutramine is a norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
What does 15 mg of slimex do for You?
Slimex 15 mg is an anorectic drug suppressing appetite by acting on receptors of the brain, which causes a feeling of satiation and fast energy consumption. Buy Slimex online because its capsules for slimming contain the active ingredient sibutramine at a dose of 15 mg.
Are there any side effects to taking slimex?
Slimex side effects may include heart palpitations, flushing, abnormal appetite, constipation, nausea, dry mouth, headache, and sleeplessness. What are the ingredients of Slimex? The Slimex ingredient is sibutramine. Does Slimex work? Sibutramine is a prescription weight-loss medication, so it is backed by strong clinical support.
How long does it take to lose weight with slimex?
The studies have confirmed that people who order Slimex and take sibutramine succeed to achieve loss of weight faster than usually. On average, patients manage to lose 5 – 10% of body weight during the period of 6 – 9 months of taking the drug for weight loss and slimming Slimex 15 mg. Moderate loss of weight improves health a lot.
How much does a package of slimex cost?
For a package of Slimex that contains 30 tablets, the cost is about $26.90. However, it’s important to note that this medication is no longer used. Any products available online are not likely the real thing.