Which is more effective pravastatin or atorvastatin?
Thus, atorvastatin 80 mg/day causes a greater reduction in LDL-cholesterol than pravastatin 40 mg/day, and this is associated with a reduced progression of atheroma and reduced clinical events.
Which statin has the strongest efficacy for lowering LDL?
Similarly, data from comparative trials, shown in Table 1 confirm that rosuvastatin is the most effective statin for lowering LDL-C (reduction of 63% with 40 mg daily), followed by atorvastatin, simvastatin, and pravastatin.
Which statin has the least amount of side effects 2020?
In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.
What is the most effective statin drug?
Statins lower cholesterol levels through inhibition of HMG-CoA reductase. The synthetic and natural statins have essentially equivalent efficacy at improving the lipid profile. However, in patients who do not achieve their LDL goals, atorvastatin and simvastatin may be the best choices for initial therapy.
Does Lipitor work better than pravastatin?
One comparative study found that there is no significant difference between pravastatin, simvastatin, and atorvastatin for preventing cardiovascular events. In other words, these statin drugs were similarly effective for reducing heart attacks and coronary heart disease.
Is pravastatin safer than other statins?
Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines. Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines. If you have liver problems, Pravachol (pravastatin) is the safest statin to use. It’s available as a generic.
Is pravastatin the best statin?
One of the first and best studied statins is pravastatin, which has been studied in both primary and secondary prevention trials. With 40 mg pravastatin daily, total cholesterol can be reduced by 25-34% with a very consistent risk reduction of 24% of death from cardiovascular diseases.
What is the difference between atorvastatin and pravastatin?
Both pravastatin and atorvastatin are medications used to reduce high levels of cholesterol. However, they are not the same. Atorvastatin is primarily metabolized by the CYP P450 enzyme system in the liver while pravastatin is broken down in the stomach.
Is pravastatin a good statin?
Is pravastatin weaker than other statins?
Pravachol (pravastatin) can improve cholesterol, but it’s not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.
Is pravastatin 10 mg effective?
Results from this study confirmed that a low dose (10 mg) of pravastatin daily is a safe and effective method of reducing plasma total and LDL-cholesterol in hypercholesterolemic, hypertensive elderly patients who are on concurrent antihypertensive drug therapy.
Is 20 mg of pravastatin effective?
Conclusions: Despite the decreased statistical power due to its premature stopping, the results of the GISSI-P suggest that a low-dose treatment with pravastatin (20 mg daily) is effective in reducing blood lipids, and underline the importance of long-term compliance with treatments in the search for a maximal …
What is the difference between atorvastin and Lipitor?
Atorvastatin Remove Atorvastatin from your drug comparison. Lipitor atorvastatin Remove Lipitor from your drug comparison. Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain.
What are the side effects of Lipitor?
Common side effects of Lipitor include: hemorrhagic stroke, arthralgia , diarrhea, and nasopharyngitis. Other side effects include: urinary tract infection, insomnia, limb pain, muscle spasm, musculoskeletal pain, myalgia, and nausea.
Is there a generic drug available for Lipitor?
For lipitor, the generic name is atorvastatin. This is not the same as a “generic version” of a drug. In order for there to be a generic version, the brand name must have gone off-patent and another company besides the orignial manufactuer must be making the medicine.
Does Lipitor affect blood pressure?
Lipitor (generic name, atorvastatin) has a dangerous side effect, even though it is used to treat high cholesterol and can save lives. Lipitor has been linked with high blood pressure and as of January 2009, the information on this side effect was not found in patient information available on popular patient info sheets, such as Medline Plus .