What is Pulmozyme dornase alfa indicated for?
Dornase alfa is a synthetic protein that breaks down excess DNA in the pulmonary secretions of people with cystic fibrosis. Dornase alfa is used to improve lung function in people with cystic fibrosis by thinning pulmonary secretions and reducing the risk of respiratory tract infections.
How is dornase alfa administered?
PULMOZYME is administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer or an approved nebulizer system [see Clinical Studies and DOSAGE AND ADMINISTRATION].
What drug class is dornase alfa?
Dornase alfa is a medication used in the management and treatment of cystic fibrosis. It is in the category B class of drugs. This activity outlines the indications, action, and contraindications for dornase alfa as a valuable agent in the therapy for cystic fibrosis, pleural effusion, and emphysema.
Does dornase alfa have many adverse effects?
If you experience any of the following serious side effects while taking dornase alfa, seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); increased difficulty breathing; chest pain; or.
Is dornase alfa expensive?
Pulmozyme (dornase alfa) works well to thin your mucus and help you breathe easier, but it is very expensive and requires a nebulizer. Works well to thin the mucus in your lungs and help clear your airways. Side effects are mild and short-lived.
What is dornase alfa solution used for?
When should I take dornase alfa?
Dornase alfa comes as a solution to inhale by mouth. It usually is taken one or two times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use dornase alfa exactly as directed.
How much does Trikafta cost?
Cystic Fibrosis sufferers are calling for ‘life changing’ drug Trikafta to be added to the PBS. The medicine currently costs patients nearly $300,000 per year.
Is there a generic for Pulmozyme?
Pulmozyme (dornase alfa) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.
When do you use dornase alfa?
Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up.
Is dornase alfa a mucolytic?
Dornase alfa (Pulmozyme®) is an inhaled medication that thins mucus. Sometimes referred to as a mucolytic or DNase, dornase alfa acts like scissors by cutting up the long DNA strands contained in white blood cells.
How much Dornase alfa is in a Pulmozyme solution?
PULMOZYME is a sterile, clear, colorless, highly purified solution in single-use ampules. Each ampule delivers 2.5 mL of the solution to the nebulizer bowl. Each mL of aqueous solution contains 1 mg dornase alfa, calcium chloride dihydrate (0.15 mg) and sodium chloride (8.77 mg). The solution contains no preservative.
How is Dornase alfa used to treat cystic fibrosis?
PULMOZYME® (dornase alfa) is indicated for daily administration in conjunction with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function. In CF
What happens if you miss a dose of Dornase alfa?
MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up. STORAGE: Store in the refrigerator between 36-46 degrees F (2-8 degrees C) away from light. Do not freeze.
How many mg of Dornase alfa are in a foil pouch?
30 unit cartons containing 5 foil pouches of 6 single-use ampules. Each 2.5 mL ampule contains 2.5 mg of dornase alfa (1 mg/mL): NDC 50242-100-40. Store PULMOZYME under refrigeration (2°C to 8°C/36°F to 46°F) in their protective foil to protect from light.