What is apicoplast in Plasmodium?

What is apicoplast in Plasmodium?

An apicoplast is a derived non-photosynthetic plastid found in most Apicomplexa, including Toxoplasma gondii, Plasmodium falciparum and other Plasmodium spp. ( parasites causing malaria), but not in others such as Cryptosporidium.

How is Plasmodium falciparum classified?

The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease’s most dangerous form, falciparum malaria….

Plasmodium falciparum
Phylum: Apicomplexa
Class: Aconoidasida
Order: Haemospororida
Family: Plasmodiidae

Does Plasmodium have apicoplast?

The malaria parasite, Plasmodium falciparum, harbours a relict plastid known as the ‘apicoplast’. The discovery of the apicoplast ushered in an exciting new prospect for drug development against the parasite.

What group does Plasmodium falciparum belong to?

phylum Apicomplexa
Plasmodium belongs to the phylum Apicomplexa, a taxonomic group of single-celled parasites with characteristic secretory organelles at one end of the cell. Within Apicomplexa, Plasmodium is within the order Haemosporida, a group that includes all apicomplexans that live within blood cells.

What is apicoplast genome?

Apicoplast, a nonphotosynthetic plastid derived from secondary symbiotic origin, is essential for the survival of malaria parasites of the genus Plasmodium. However, the complete apicoplast genome is available for only the most virulent human malaria parasite, Plasmodium falciparum.

What classification is a Plasmodium?

Aconoidasida
Plasmodium/Class

What is Plasmodium Class 11?

Hint: Plasmodium is a parasite and is the causative organism of malaria. It requires two hosts to complete its life cycle- female Anopheles mosquito and human beings. When the female anopheles mosquito bites a healthy, human being, the person suffers from malaria that can become severe with time.

What class is Plasmodium?

What is an apicoplast and where did it come from evolutionarily )?

The apicoplast is a relict, non-photosynthetic plastid found in Apicomplexa, including malaria parasites such as Plasmodium falciparum. It is proposed that it evolved via secondary endosymbiosis and is surrounded by four membranes with the outermost part of the endomembrane system.

What is the role of apicoplast in Plasmodium?

Apicoplast, a nonphotosynthetic plastid derived from secondary symbiotic origin, is essential for the survival of malaria parasites of the genus Plasmodium. Elucidation of the evolution of the apicoplast genome in Plasmodium species is important to better understand the functions of the organelle.

How big is the genome of Plasmodium falciparum?

The 35-kb circular apicoplast genome of Plasmodium falciparum, the most virulent human malaria parasite, possesses translation- and transcription-related protein genes, rRNAs, tRNAs, and several other genes. Elucidation of the evolution of the apicoplast is important to better understand the functions of the organelle.

What kind of metabolic pathways does the apicoplast have?

Widely found in apicomplexan parasites, the apicoplast is a nonphotosynthetic plastid, a product of secondary endosymbiosis of algal origin ( McFadden 2011 ). The plastid retains critical metabolic pathways such as type II fatty acid synthesis, isoprenoid synthesis, and heme synthesis.

Why is the apicoplast an attractive drug target?

The apicoplast is involved in the synthesis of lipids and several other compounds and provides an attractive drug target.

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