How many cases of MDS per year?

The incidence of MDS increases markedly with age, and the disease is most prevalent in individuals who are white and male. It is conservatively estimated that >10,000 new cases of MDS occur in the United States annually, and that ≥60,000 individuals with MDS currently reside in the country.

What is the incidence of MDS?

If you look at the most recent SEER [Surveillance, Epidemiology, and End Results Program] Registry data, the incidence per year for MDS is 4.9 per 100,000 people. The interesting thing about MDS is there is a close association between increasing age and increasing incidence.

Are myelodysplastic syndromes rare?

Myelodysplastic syndromes (MDS) are a rare group of blood disorders that occur as a result of disordered development of blood cells within the bone marrow. The three main types of blood elements (i.e., red blood cells, white blood cells and platelets) are affected.

Who is most likely to get MDS?

MDS occurs most often in people older than 60 and is less common in younger people. MDS is rare in children. Gender. Men develop MDS more often than women.

Is MDS a death sentence?

MDS is a potentially fatal disease; the common causes of death in a cohort of 216 MDS patients included bone marrow failure (infection/hemorrhage) and transformation to acute myeloid leukemia (AML).

Is MDS a terminal disease?

MDS is a form of bone marrow cancer, although its progression into leukaemia does not always occur. The failure of the bone marrow to produce mature healthy cells is a gradual process, and therefore MDS is not necessarily a terminal disease. In some patients, however, MDS can progress to AML, Acute Myeloid Leukaemia.

How often is MDS misdiagnosed?

Preliminary results from a national registry. Preliminary data from a national registry shows that as many as 40 percent of patients diagnosed with myelodysplastic syndromes (MDS) don’t actually have the disorder.

Can you live a normal life with MDS?

The following survival statistics are based on the revised International Prognostic Scoring System (IPSS-R) risk groups….Survival statistics for MDS.

WPSS Risk Group	Median Survival	Risk of AML (within 5 years)
Low	5.5 years	14%
Intermediate	4 years	33%
High	2.2 years	54%
Very high	9 months	84%

Is myelodysplasia a death sentence?

Can you live a full life with MDS?

With current treatments, patients with lower-risk types of some MDS can live for 5 years or even longer. Patients with higher-risk MDS that becomes acute myeloid leukemia (AML) are likely to have a shorter life span. About 30 out of 100 MDS patients will develop AML.

Can you live 20 years with MDS?

Can you have MDS with normal blood counts?

Many people who are diagnosed with MDS go to their doctor with some or all of the symptoms typical of MDS. Other people are diagnosed with MDS even though they don’t have any symptoms. They may go to their doctor for a routine checkup and mild blood-count abnormalities are found in their blood work.

How many people are diagnosed each year with myelodysplastic syndromes?

Key Statistics for Myelodysplastic Syndromes. The number of people diagnosed with myelodysplastic syndromes (MDS) in the United States each year is not known for sure. Some estimates have put this number at about 10,000, while other estimates have been much higher.

What causes death from myelodysplastic syndrome ( MDS )?

Death from MDS is often caused by bleeding and/or infection from low blood cell counts or after the disease becomes acute myeloid leukemia (AML). About a third of patients with MDS develop AML. It is important to remember that statistics on MDS are an estimate.

How many people are diagnosed with MDS each year?

Some estimates have put this number at about 10,000, while other estimates have been much higher. MDS is uncommon before age 50, and the risk increases as a person gets older. It is most commonly diagnosed in people in their 70s. The number of new cases diagnosed each year is likely increasing as the average age of the US population increases.