What is the use of Tolinase?
Tolinase (tolazamide) is an oral diabetes medicine used together with diet and exercise to treat type 2 (non-insulin dependent) diabetes. Other diabetes medicines are sometimes used in combination with Tolinase if needed.
What is use of Glimepiride?
Glimepiride is a medicine used to treat type 2 diabetes. Type 2 diabetes is a condition where the body doesn’t make enough insulin, or the insulin that it makes doesn’t work properly. This can cause high blood sugar levels (hyperglycaemia).
Why are second generation sulfonylureas preferred over first generation sulfonylureas?
The second generation sulfonylureas have largely replaced the first generation agents in routine use, because they are more potent, can be administered in lower doses, and can be given on a once daily basis.
Which is better glimepiride or metFORMIN?
Metformin was not better than glimepiride in overall efficacy in controlling the levels of HbA1c, postprandial blood sugar (PPBS), fasting plasma insulin (FINS), systolic and diastolic blood pressures (SBP and DBP), and high density lipoprotein (HDL).
Why is tolbutamide used?
Tolbutamide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
What do second-generation sulfonylureas do?
The second-generation sulfonylureas include glipizide (Glucotrol and Glucotrol XL), glyburide (Diabeta, Micronase, and Glynase PresTab), and glimepiride (Amaryl). These drugs are effective in rapidly ‘lowering blood sugar but run the risk of causing hypoglycemia.
Why sulfonylureas are not useful in Type 1 Diabetes?
Medical uses. Sulfonylureas are used primarily for the treatment of diabetes mellitus type 2. Sulfonylureas are ineffective where there is absolute deficiency of insulin production such as in type 1 diabetes or post-pancreatectomy. Sulfonylureas can be used to treat some types of neonatal diabetes.
How is Orinase used to treat type 2 diabetes?
Orinase is a used to treat type 2 diabetes. Orinase belongs to a group of drugs called sulfonylureas, which help to lower blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body).
How are tolinase tablets used to treat type 2 diabetes?
Tolinase Tablets are indicated as an adjunct to diet to lower the blood glucose in patients with noninsulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone.
What kind of powder is in tolinase tablets?
Tolinase Tablets contain tolazamide, an oral blood glucose lowering drug of the sulfonylurea class. Tolazamide is a white or creamy-white powder with a melting point of 165° to 173° C. The solubility of tolazamide at pH 6.0 (mean urinary pH) is 27.8 mg per 100 mL.
Are there any side effects to taking Orinase?
Tell your doctor right away if you have any serious side effects, including: dark urine, easy bleeding/bruising, persistent nausea, severe stomach/abdominal pain, signs of infection (such as persistent sore throat, fever), yellowing eyes/skin.