How do you calculate cystatin C?
(iv) GFR calculated according to CKD-EPI creatinine and cystatin formula: 177.6 × ( serum creatinine ( mg dL ) ) − 0.65 × ( serum cystatin C ( mg L ) ) − 0.57 × age − 0.2 . The correction factor of 0.82 was used for women.
What is EGFR cystatin C?
Cystatin C is a protein that is produced by the cells in your body. If the level of cystatin C in your blood is too high, it may mean that your kidneys are not working well. A blood test for cystatin C can help your healthcare provider find your GFR (glomerular filtration rate).
Can you raise your GFR by drinking water?
Water ingestion can acutely affect GFR, although not necessarily in the direction one might expect. Using 12 young, healthy individuals as their own controls, Anastasio et al. found increased water intake actually decreases GFR.
When to use cystatin C or creatinine equation?
For use in patients with stable kidney function. While the combined creatinine and cystatin C equation can add accuracy, cystatin c is not available in all laboratories and the creatinine-based equation is adequate for most clinical purposes. Patients with chronic kidney disease (not acute), to measure renal function.
How to calculate GFR from serum cystatin C?
Estimation of GFR from Serum Cystatin C: The good correlation allows close estimation of GFR *Inulin clearance and serum Cystatin C testing in 209 patients with a broad range of GFR, age and different pathologies yielded the following correlation function for calculation of estimated GFR: Reference Range for Cystatin C:≤0.95 mg/l in Men & Women
Which is the best GFR calculator for kidney function?
GFR Calculator. Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age. The National Kidney Foundation recommends using the CKD-EPI Creatinine Equation (2009) to estimate GFR. For persons under 18 years of age, use the pediatric GFR calculator.
Is the CKD-EPI equation based on serum creatinine?
The CKD-EPI Creatinine Equation for Glomerular Filtration Rate (GFR) estimates GFR based on serum creatinine. MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice.