What does wobble mean in genetics?
Describes the redundancy in the genetic code such that the same amino acid may be encoded by multiple codons.
What is an example of a wobble biology?
The existence of wobble minimizes the damage that can be caused by a misreading of the code; for example, if the Leu codon CUU were misread CUC or CUA or CUG during transcription of mRNA, the codon would still be translated as Leu during protein synthesis.
What is a wobble mutation?
A wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules. The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C).
What is wobble effect or phenomenon?
The wobble hypothesis deals with the phenomenon of degeneracy that is seen in the genetic code through tRNA recognition of more than one codon. Each tRNA contains a triplet anti-codon that is complementary to a codon in mRNA.
What is wobble in protein synthesis?
“Wobble” “Wobble” Pairing of the tRNA anticodon with the mRNA codon proceeds from the 5′ end of the codon. In this example, the double-ringed G can pair with either a single-ringed U or C.
Who explained the wobble hypothesis Mcq?
Explanation: In 1966, Francis Crick devised the wobble hypothesis to explain the observations regarding base pairing. It states that the base at the 5′ end of the anticodon is not as spatially confined as the other two, allowing it to form hydrogen bonds with any of the several bases located at the 3′ end of a codon.
How does wobble work?
The wobble position of a codon refers to the 3rd nucleotide in a codon. This nucleotide has two major characteristics: Binding of a codon in an mRNA the cognate tRNA is much “looser” in the third position of the codon. This permits several types of non-Watson–Crick base pairing to occur at the third codon position.
What is wobble translation?
What is wobble effect in prestressed concrete?
If the profile of cable is linear, the loss will be due to straightening or stretching of the cables called Wobble Effect. • If the profile is curved, there will be loss in stress due to friction between tendon and the duct or between the tendons themselves.
What is wobble and how does it accommodate fidelity in the genetic code?
Wobble hypothesis: The hypothesis states that the first two positions of the codon-anticodon interactions will have normal Watson-Crick base-pairing but the third position has more ‘leeway’ and it can accommodate small amount of ‘play’ or ‘wobble’ to allow for limited conformation adjustments during pairing.
What is wobble in mRNA?
What are mRNA codons?
A mRNA codon is a 3 base pair long part of the mRNA that codes for a specific amino acid in the ribosomes of a cell.
What is the significance of wobble?
Wobble base pairs are fundamental in RNA secondary structure and are critical for the proper translation of the genetic code. Wobbling allows faster dissociation of tRNA from mRNA and also protein synthesis. The existence of wobble minimizes the damage that can be caused by a misreading of the code; for example,…
What is wobble in genetics?
Wobble or wobbles may refer to: “Wobble” (song), a single by V.I.C. Wobbles (equine disorder), a disorder of the nervous system in dogs and horses Wobble base pair, a type of base pairing in genetics Jah Wobble (born 1958), British musician Milankovitch wobble, change in the Earth’s axial tilt, axial precession…
What is the wobble position?
The wobble position of a codon refers to the 3rd nucleotide in a codon. This nucleotide has two major characteristics:
What is Wobble DNA?
Wobble is where the third nucleotide in a codon can match up with more than one first nucleotide in the tRNA’s anticodon. For example, if the tRNA’s first nucleotide is a G, it can match with either C or U in the third codon position.