What is nifedipine ER 90 mg used for?
Nifedipine is used alone or in combination with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used for certain types of chest pain (angina).
When is the best time of day to take nifedipine?
You can take nifedipine at any time of day, but try to make sure it’s around the same time or times every day. Swallow the capsules or tablets whole with a drink of water. Do not break, crush, chew or open up the capsules unless your doctor or pharmacist has said you can.
When should you not take nifedipine?
You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks.
How quickly does nifedipine lower blood pressure?
6. Response and effectiveness. Nifedipine is quickly absorbed when taken orally and peak blood levels occur in approximately 30 minutes. It is relatively short-acting and needs to be taken three times a day.
What medications should not be taken with nifedipine?
Strong CYP3A inducers, such as rifampin, rifabutin, phenobarbital, phenytoin, carbamazepine, and St. John’s Wort reduce the bioavailability and efficacy of nifedipine; therefore nifedipine should not be used in combination with strong CYP3A inducers such as rifampin (See CONTRAINDICATIONS).
Why is nifedipine taken at night?
Overnight blood pressure control is important in order to lower your risk. If your medication wears off before your next dose is due, your blood pressure may be elevated for several hours while you sleep. You may also wake with high blood pressure. Taking your medication at bedtime may help prevent this issue.
Is nifedipine bad for your kidneys?
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.
Is NIFEdipine bad for your kidneys?
What foods should be avoided when taking NIFEdipine?
NIFEdipine food You should avoid or limit the consumption of grapefruit and grapefruit juice if you are receiving treatment with NIFEdipine. Grapefruit juice can significantly increase the blood levels and effects of medications like NIFEdipine.
What foods should be avoided when taking nifedipine?
Are there any side effects to taking isoflavones?
Allergic reactions (involving rash, itching, and in severe instances, anaphylaxis) Swelling of the ankles and abdominal tenderness have been noted in high doses of isoflavones of four to eight milligrams per kilograms (mg/kg).
How big is the molecular weight of nifedipine?
Nifedipine is a yellow crystalline substance, practically insoluble in water but soluble in ethanol. It has a molecular weight of 346.3. Nifedipine extended release tablets are formulated as Nifedipine GITS (Gastrointestinal Therapeutic System).
What are the biological effects of isoflavone in the body?
Multiple biological actions of isoflavones, such as favorable effect on the blood lipid profile and inhibition of LDL cholesterol oxidation, may lead to cardio protective effects. [DB01645] has been shown to have antioxidant properties on hydrogen peroxide production _in vitro_ and blocks the formation of oxygen free radicals.
How are nifedipine extended release tablets pharmacokinetics?
Pharmacokinetics of nifedipine extended release tablets are linear over the dose range of 30 to 180 mg in that plasma drug concentrations are proportional to dose administered. There was no evidence of dose dumping either in the presence or absence of food for over 150 subjects in pharmacokinetic studies.