How are dengue viruses classified?
Dengue is classified as (1) undifferentiated fever, (2) dengue fever (DF), and (3) dengue hemorrhagic fever (DHF). In addition to fever and at least 2 clinical findings, diagnosis of DF requires epidemiological or laboratory evidence supporting a dengue virus infection.
Which dengue serotype is most common?
Serotyping revealed that DENV-1 was the most common form (41%) followed by DENV-2 (31%), DENV-3 (20%), and DENV-4 (7%) [15].
What is the epidemiology of dengue fever?
The proportion of laboratory confirmed dengue patients in different age groups ranged between 19.1% among persons to 60 years or older and 31.8% among those aged between 10–19 years (Table 1). Of the 60,096 laboratory confirmed patients, 65% were aged 20 years or more.
WHO dengue 2009 classification?
Dengue classification according to the World Health Organization guidelines issued in 2009. Dengue is classified as dengue with or without warning signs and severe dengue. Diagnosis of dengue requires the presence of fever and at least 2 clinical findings or any warning signs.
How many variants of dengue are there?
There are four dengue virus serotypes: DENV-1, DENV-2, DENV-3, and DENV-4. They belong to the genus Flavivirus, family Flaviviridae (of which yellow fever virus is the type species), which contains approximately 53 viruses. The flaviviruses are relatively small (40–65 nm) and spherical with a lipid envelope.
What is the difference between the 4 dengue serotypes?
All Answers (3) The difference is based on antibody reactions to surface antigens on the virus. Each serotype has subtle differences in their surface proteins, meaning that different antibodies are produced to bind to those proteins.
Is DENV-1 The most common dengue virus?
DENV-2 had the highest proportion of males (74.3%) compared with DENV-1 (68.5%) and DENV-3 (58.8%). Secondary cases were more common among DENV-2 cases (60.8%) followed by DENV-1 (53.1%) and DENV-3 (46.3%).
How many types of dengue fever are there?
There are four serotypes (DENV-1, -2, -3, and -4), and the virus is transmitted to humans through the bite of mosquitoes of the genus Aedes (5). DENV causes a wide spectrum of clinical manifestations, from DF to dengue hemorrhagic fever (DHF), which may progress to dengue shock syndrome (DSS) (20, 43).
What is dengue Slideshare?
INTRODUCTION Dengue fever is a painful debilitating mosquito born disease caused by any one of four closely related dengue virus. 3. DEFINITION • Dengue fever is also known as breakbone fever is a mosquito born tropical disease caused by the mosquito bite.
How many serotype of dengue virus are there?
The virus responsible for causing dengue, is called dengue virus (DENV). There are four DENV serotypes, meaning that it is possible to be infected four times. While many DENV infections produce only mild illness, DENV can cause an acute flu-like illness.
What are the different types of dengue disease?
Dengue fever, the most prevalent arthropod-borne viral disease in humans, has been conventionally classified into four main categories: non-classical, classical, dengue hemorrhagic fever, and dengue shock syndrome. Several studies reported lack of correlation between the categories of the conventional classification and the disease severity.
Where was the largest number of dengue cases reported?
The largest number of dengue cases ever reported globally was in 2019. All WHO Regions were affected, and dengue transmission was recorded in Afghanistan for the first time. The American Region alone reported 3.1 million cases, with more than 25,000 classified as severe.
Are there any competing interests with dengue fever?
Competing interests: The authors have declared that no competing interests exist. Dengue fever (DF) is the most prevalent arthropod-borne viral disease in humans and one of the major re-emerging communicable diseases.
How many cases of dengue in Saudi Arabia?
This retrospective study involved 357 laboratory-confirmed cases of dengue infection diagnosed at King Abdulaziz University Hospital, Jeddah, Saudi Arabia over a 4-year period from 2014 to 2017. The sensitivity of the new classification for identifying severe cases was limited (65%) but higher than the old one (30%).