What is Uniport database?

What is Uniport database?

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.

What databases can be searched using UniProt?

The UniProt website provides ten main datasets and three main tools. The key UniProt datasets are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), the UniProt Archive (UniParc) and protein sets for completely sequenced genomes (Proteomes).

Is UniProt and SwissProt same?

UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProtKB/TrEMBL is a computer-annotated (unreviewed) supplement to Swiss-Prot, which strives to gather all protein sequences that are not yet represented in Swiss-Prot.

Does UniProt have an API?

UniProt provides several application programming interfaces (APIs) to query and access its data programmatically. Data is available in all formats provided on the website, e.g. text, XML, RDF, FASTA, GFF, tab-separated for UniProtKB protein data.

What is the difference between Swiss Prot and TrEMBL?

TrEMBL is a computer-annotated supplement of SWISS-PROT that contains all the translations of EMBL nucleotide sequence entries, which are not yet integrated in SWISS-PROT. Currently, SWISS-PROT and TrEMBL have 0.5 and 7.6 million sequences, respectively.

How is Swiss-Prot different from TrEMBL?

TrEMBL consists of entries in a SWISS-PROT format that are derived from the translation of all coding sequences in the EMBL nucleotide sequence database, that are not in SWISS-PROT. Unlike SWISS-PROT entries those in TrEMBL are awaiting manual annotation.

Is Swiss-Prot a primary database?

SWISS PROT is a protein sequence database. Annotations in the database provide all the information regarding the structure and function of a particular protein along with its functions and modifications if any. The data is all primary and easily accessible. It is thus a primary database.

How do you retrieve a protein sequence from UniProt?

Retrieving sequences from the website

1. Perform your favorite query and view the resulting list of entries (e.g. this query retrieves all UniProtKB entries that are part of the human proteome: proteome:UP000005640)
2. Click the Download button in the query result page.

What is TrEMBL?

TrEMBL, (Translated EMBL) is a very large protein database in SwissProt format generated by computer translation of the genetic information from the EMBL Nucleotide Sequence Database database. In contrast to SwissProt which contains only proteins actually found in the wild, and PIR which is entirely unchecked.

Is SWISS-PROT a secondary database?

How do I access SWISS-PROT?

There are multiple sites on the Web that can access the Swiss-Prot/TrEMBL and retrieve the database. Its main sites are the ExPASy Molecular Biology website (http://www.expasy.org/) and the European Institute of Bioinformatics (EBI) website (http://www.ebi.ac.uk/swissprot/).

What are the names of the UniProt databases?

The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). The UniProt consortium and host institutions EMBL-EBI, SIB and PIR are committed to the long-term preservation of the UniProt databases.

How is uniprotein used as a protein supplement?

Uniprotein ® is a protein-rich biomass (approximately 72% protein) and can be used as a direct supplement in animal feed compounds. Uniprotein ® takes the form of a free-flowing reddish brown, granule with a particle size of 150-200 μm. It has a long shelf life, and the production process always results in a uniform product.

Is the UniProt database redundant or non redundant?

UniProt Archive (UniParc) is a comprehensive and non-redundant database, which contains all the protein sequences from the main, publicly available protein sequence databases. Proteins may exist in several different source databases, and in multiple copies in the same database.

What is the purpose of the UniProt project?

The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.