What is the difference between primary and post primary TB?

What is the difference between primary and post primary TB?

Primary TB stimulates systemic immunity that kills organisms and heals granulomas resulting in both protection from disseminated TB and resistance to new infection. Post primary TB, in contrast, requires systemic immunity that it subverts to produce local susceptibility in the apex of the lung.

Is post primary TB the same as secondary TB?

Post-primary tuberculosis, also known as reactivation tuberculosis or secondary tuberculosis is perhaps more correctly designated “tuberculosis in an immunocompetent host” 1. The features are distinctly different to so-called primary tuberculosis which occurs in the absence of immunity.

Is post primary TB infectious?

Post primary tuberculosis is typically restricted to the upper lobes of the lungs and does not involve lymph nodes or other organs. About 90% of cases recover spontaneously without therapy. However those that become ill account for 80% of all clinical cases and nearly 100% of transmission of infection.

How soon after primary TB can disseminated TB occur?

Disseminated disease can occur within weeks of the primary infection. Sometimes, it does not occur until years after you become infected. You are more likely to get this type of TB if you have a weakened immune system due to disease (such as AIDS) or certain medicines. Infants and older adults are also at higher risk.

What is primary TB infection?

Primary TB is defined as infection in a patient who has never been treated for TB or taken anti-TB treatment for less than one month [2].

Why does TB affect upper lobes?

Recurrent tuberculosis (reinfection and postprimary tuberculosis due to reactivation) predominantly involves the apical and posterior segments of the upper lobes and the superior segments of the lower lobes because of the relatively higher oxygen tension and delayed lymphatic drainage in these areas.

Why is tuberculosis common in the upper lobe?

Is disseminated TB treatable?

Disseminated tuberculosis is treated with a combination of antibiotics. This is the same treatment for tuberculosis in the lungs, but disseminated TB usually needs a longer course of antibiotics. It may take 6 to 12 months to completely treat the infection.

Is there a cure for tuberculosis in 2021?

There is no cure for TB This is false; TB is treatable. The most common treatment for a latent TB infection is the antibiotic isoniazid.