What is a common adverse reaction among Antilipemic medications?
Adverse Effects
| BODY SYSTEM | ADVERSE EFFECTS |
|---|---|
| Central nervous | Headache, dizziness, blurred vision, fatigue, insomnia |
| Gastrointestinal | Constipation, diarrhea, nausea |
| Other | Myalgias, skin rashes |
What is a Antilipemic used for?
Antilipemic agents are beneficial in lowering blood cholesterol profiles, thereby possibly reducing the rate of first major vascular events.
What is an example of Antilipemic?
Seven statins are available in the United States: lovastatin (Mevacor: 1987), pravastatin (Pravachol: 1991), simvastatin (Zocor: 1991), fluvastatin (Lescol: 1993), atorvastatin (Lipitor: 1996), rosuvastatin (Crestor: 2003) and pitavastatin (Levalo: 2009).
What class of drugs are Antilipemic?
The medications for dyslipidemia can be grouped into five categories: fibrates, bile acid resins, hydroxymethylglutaryl co-enzyme A (HMG-CoA) reductase inhibitors (known collectively as statins), proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and miscellaneous agents.
What is the desired effect of any Antilipemic therapy?
Therapeutic Effect: Decreases low-density lipoprotein (LDL) cholesterol, very low-density lipoprotein (VLDL), and plasma triglyceride levels; increases high-density lipoprotein (HDL) concentration.
What are the expected side effects of fibric acid derivatives?
The side effects of fibrates include nausea, stomach upset, and sometimes diarrhea. Fibrates can irritate (inflame) the liver. The liver irritation usually is mild and reversible, but it occasionally can be severe enough to require stopping the drug.
What is Antilipemic therapy?
These medications usually lower low-density lipoprotein (LDL) cholesterol levels. In addition, they sometimes lower triglyceride (TG) levels and may modestly elevate high-density lipoprotein (HDL) cholesterol levels. Antilipemic agents may be of value to patients with hypoalphalipoproteinemia (HA).
How do Antilipemic drugs work?
It works inhibiting microsomal triglyceride transfer protein. It is the first in a new class of lipid-lowering agents to improve lipoproteins (total cholesterol, low-density lipoprotein, and nonhigh-density lipoprotein cholesterol and (apo B) in patients.
Which Antilipemic causes myopathy?
Gemfibrozil co-administration with statins leads to increased risk of myopathy.
Which Antilipemic drug acts by blocking the absorption of cholesterol from the small intestine?
Ezetimibe lowers LDL-C levels by approximately 20% by inhibiting cholesterol absorption by the intestines leading to the decreased delivery of cholesterol to the liver, a decrease in hepatic cholesterol content, and an up-regulation of hepatic LDL receptors.
Which conditions are the serious adverse effects of fibric acids?
The adverse effects of fibric acids vary depending on the particular agent selected for the patient. Some of the most common adverse effects include headache, dizziness, back pain, diarrhea, dyspepsia, nasopharyngitis, sinusitis, and abnormal liver function tests.
Are there any contraindications to the use of BiPAP?
Contraindications for BiPAP include. Inability of patient to protect own airway (decreased level of consciousness). This includes the inability of the patient to pull off the mask if it becomes full of fluid, such as vomit or spit. Increased secretions (i.e. pulmonary edema, increased sputum production)
Can a BiPAP mask be used after stomach surgery?
This includes the inability of the patient to pull off the mask if it becomes full of fluid, such as vomit or spit. Any patient at risk of vomiting (post stomach surgery, drug overdose). In this case you may be able to use BiPAP if an NG is inserted.
When to use sedation for BiPAP tolerant patients?
If the patient can’t tolerate BiPAP due to anxiety, it may be worth using sedation to facilitate BiPAP tolerance. Sedation is particularly useful for patients with COPD or asthma, who require a slow respiratory rate in order to exhale properly:
Can a COPD patient be on BiPAP while on HFNC?
Sometimes, it is possible to maintain a patient on BiPAP with occasional breaks on HFNC for secretion clearance (e.g. a COPD patient with mild secretions). However, for a patient with copious secretions, BiPAP is contraindicated.