How common is HHV-7?
HHV-7 is ubiquitous and infects more than 80% of children in infancy. It has been implicated in the etiology of pityriasis rosea (see p. 100), but reactivation of the virus is a possible explanation for its occurrence in some cases.
What does HHV 6 stand for?
Infections with human herpesvirus 6 (HHV-6), a ß-herpesvirus of which two variant groups (A and B) are recognized, is very common, approaching 100% in seroprevalence. Primary infection with HHV-6B causes roseola infantum or exanthem subitum, a common childhood disease that resolves spontaneously.
What disease is caused by HHV 6?
Roseola, also called exanthem subitum and sixth disease, is a common, contagious viral infection caused by the human herpesvirus (HHV) 6. This strain of the herpes virus is different than the one that causes cold sores or genital herpes infections. Roseola occurs most often in children aged 6 to 24 months.
What are HHV 6 symptoms?
HHV-6 B
- Sudden high fever (above 103 F) lasting three to five days.
- Mild sore throat.
- Runny nose.
- Cough.
- Swollen lymph nodes in the neck.
- Irritability.
- Mild diarrhea.
- Decreased appetite.
How common is hhv6?
HHV-6B infects nearly 100% of human beings, typically before the age of three and often results in fever, diarrhea, sometimes with a rash known as roseola. Although rare, this initial infection HHV-6B infection can also cause febrile seizures, encephalitis or intractable seizures.
Is roseola a HSV?
Roseola is a childhood illness caused by two strains of herpes virus. Common signs of roseola are fever and a rash on the trunk and neck.
Which is the best description of HHV-6B?
HHV-6A and HHV-6B were recognized by the International Committee on Taxonomy of Viruses (ICTV) as distinct species in 2012. Human Roseoloviruses include HHV-6A, HHV-6B and HHV-7. Herpesvirus was established as a genus in 1971 in the first report of the ICTV. This genus consisted of 23 viruses among 4 groups.
What are the effects of HHV-6 in humans?
In these patients, HHV-6 infection or reactivation may result in bone marrow suppression, pneumonitis, encephalitis, encephalopathy, hepatitis, fever, and skin rash or may complicate engraftment of the transplanted organ and culminate in rejection and death.
What is the diameter of a HHV-6 virion?
The diameter of an HHV-6 virion is about 2000 angstroms. The virion’s outer portion consists of a lipid bilayer membrane that contains viral glycoproteins and is derived from that of the host. Below this membrane envelope is a tegument which surrounds an icosahedral capsid, composed of 162 capsomeres.
What are the symptoms of HHV-6B in children?
These include hepatitis, febrile convulsions, and encephalitis. Children who suffer from exanthema subitum, caused by an HHV-6B infection, experience fevers lasting 3 to 5 days; rashes on the torso, neck, and face; and sometimes febrile convulsions, however, the symptoms are not always present together.