What is a FibroTest ActiTest panel?
FibroTest-ActiTest estimates the levels of fibrosis and cirrhosis in the liver as well as the level of necroinflammatory activity.
What is included in a liver fibrosis panel?
The enhanced liver fibrosis (ELF) is a serological panel including hyaluronic acid (HA), tissue inhibitor of matrix metalloproteinases-1 (TIMP-1), and amino-terminal propeptide of type III procollagen (PIIINP) that has shown good results in predicting liver fibrosis in distinct scenarios of chronic liver diseases.
What is a FibroTest?
FibroTest is another biomarker test that uses the combination of age and gender of the patient with alanine aminotransferase (ALT), alpha-2-macroglobulin (α-2-M), haptoglobin, apolipoprotein A-1 (Apo-A1), bilirubin, and gamma-glutamyltranspeptidase (GGT) for the assessment of fibrosis.
How liver fibrosis test is done?
Ultrasound elastography is a special ultrasound technique to test for liver fibrosis. The movement of the liver caused by ultrasound wave is measured in the middle of the liver, and its stiffness (or elasticity) is calculated. Fibrotic livers are stiffer and moves to a greater degree compared to normal livers.
How accurate is a FibroTest?
| Overall cohort | Sensitivity | Specificity |
|---|---|---|
| FibroTest ≥0.58 – ITDa | 67% (54–78) | 87% (82–91) |
| FibroTest ≥0.58 – per protocol | 67% (54–78) | 89% (84–93) |
| TE ≥15 kPa – ITDb | 86% (75–93) | 94% (90–96) |
What is a normal Hepascore?
These markers along with age and sex are applied to an equation and a score of between 0 and 1.0 is calculated: <0.50: significant fibrosis is absent. ≥0.50: significant fibrosis present. <0.84: cirrhosis is absent. ≥0.84: cirrhosis is likely present.
What do FibroScan numbers mean?
FibroScan measures scarring by measuring the stiffness of your liver. The fibrosis result is measured in kilopascals (kPa) It’s normally between 2 and 6 kPa. The highest possible result is 75 kPa. Many people with liver disease(s) have a result that’s higher than the normal range.