What is the role of ambroxol?
Ambroxol is used in the treatment of respiratory tract disorders associated with viscid mucus. Ambroxol is a mucolytic medication. It thins and loosens mucus (phlegm) in the nose, windpipe and lungs making it easier to cough out.
What is the use of ambroxol hydrochloride drops?
Ambroxol Hydrochloride It is used to treat pathological mucus secretion disorders, allowing the patient to breathe deeply and freely. In patients with a confirmed history of gastric ulcers, it should be used with caution.
Can children take ambroxol?
Children 6-12 years: 15-30 mg 2-3 times daily PO. Children >12 years, Adolescents, Adults, and Elderly: 60-120 mg daily in 2-3 divided doses PO.
What is the side effect of Ambroxol?
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, dyspepsia, dry mouth or throat, abdominal pain, heartburn, oral or pharyngeal hypoaesthesia, dysgeusia. Potentially Fatal: Rarely, anaphylactic reactions (e.g. anaphylactic shock, angioedema, rash, urticaria, pruritus).
Is ambroxol a paracetamol?
Ambroxol is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Levocetirizine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer).
What is the mechanism of action of dextromethorphan?
Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.
Can ambroxol cause sleepiness?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as emphysema, chronic bronchitis, asthma, smoker’s cough), cough with blood or large amounts of mucus, liver problems. This drug may make you dizzy or drowsy.
What is the mechanism of action of ambroxol?
Mechanism : Ambroxol is a mucolytic. It breaks down the acid mucopolysaccharide fibres which makes the sputum thinner and less viscous and therefore promotes mucus clearance. It also stimulates synthesis and release of surfactant by type II pneumocytes.
How does Ambroxol hydrochloride decrease mucus viscosity?
Ambroxol hydrochloride acts as an expectoration improver and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and by breaking network of fibres in tenacious sputum .
Why is Ambroxol considered a mucolytic agent?
Ambroxol is a mucolytic agent. Excessive Nitric oxide (NO) is associated with inflammatory and some other disturbances of airways function. NO enhances the activation of soluble guanylate cyclase and cGMP accumulation.
How does Ambroxol work as an anti glue?
Surfactant acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. Ambroxol is a potent inhibitor of the neuronal Na+ channels. This property led to the development of a lozenge containing 20 mg of ambroxol.