What is the Ganzoni formula?

What is the Ganzoni formula?

A patient’s total body iron deficit can be calculated using the Ganzoni formula (total iron dose = [actual body weight × (15-actual Hb)] × 2.4 + iron stores) [32].

How do you calculate total iron?

Body iron was calculated from the R/F ratio as follows: body iron (mg/kg) = −[log(R/F ratio) − 2.8229]/0.1207. Calibration of the ratio of serum transferrin receptor to serum ferritin with body iron. Positive values represent storage iron, and negative values indicate tissue iron deficiency.

How do you calculate iron from hemoglobin?

Background:

1. Iron deficit – equation derivation1 :
2. Assumptions: -Blood volume = 65 mL/kg. -Hgb conc target =14.0 g/dL.
3. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL)
4. Final calculations: -Hgb iron deficit (mg) = weight (kg) x (14 – Hgb) x (2.145)

How much iron infusion do I need?

The infusion will take between 15-30 minutes if it is given in amounts of 200-300 milligrams (mg). Most doctors will not recommend giving an individual more than 600 mg of iron in one week. If a person receives too much iron too quickly, they may be at greater risk for adverse side effects from the infusion.

How do you calculate iron when pregnant?

Required iron dose (mg) = (2.4 × (target Hb-actual Hb) × pre-pregnancy weight (kg)) + 1000 mg for replenishment of stores10. The required iron dose varied depending upon index Hb level and pre-pregnancy weight.

How long does it take for Monoferric to work?

INNOVATIVE MATRIX CONTROLS BIOAVAILABLE IRON RELEASE Monoferric is a 1000 mg IV IRON THAT IS FDA APPROVED FOR ONE INFUSION IN ≥20 MINUTES* that delivers a slow and controlled release of bioavailable iron for patients with IDA.

How do you calculate iron in blood?

Two thirds of body iron is present in circulating red blood cells as hemoglobin. Each gram of hemoglobin contains 3.47 mg of iron; thus, each mL of blood lost from the body (hemoglobin 15 g/dL) results in a loss of 0.5 mg of iron.

How do you calculate elemental iron content?

There are 5 Fe atoms per complex, so in 2700 mg of complex there is 7.94 x 5 x 10^-5 = 3.97 x 10^-4 moles of Fe. The mass of iron is therefore: 3.97 x 55.845 X 10^-4 = 0.02217 g of iron, so about 22 mg.

How do you calculate hemoglobin percentage?

Calculated hemoglobin: The ADVIA back-calculates a hemoglobin (calculated hemoglobin) from the CHCM (i.e. calculated hemoglobin = (CHCM x MCV x RBC count) ÷ 1000.

What is a severely low ferritin level?

Serum ferritin is typically less than 10 ng/mL in severe iron deficiency associated with anemia. In iron deficiency without anemia, ferritin is typically in the range of 10-20 ng/mL.

What ferritin level requires iron infusion?

IDA with non-dialysis CKD: serum ferritin less than 100 ng/mL or TSAT less than 20 percent. If serum ferritin is 100-300 ng/mL, TSAT less than 20 percent is required to confirm IDA. IDA with hemodialysis-dependent CKD: serum ferritin less than or equal to 200 ng/mL and TSAT less than or equal to 20 percent; or.

How do you calculate iron replacement?

The formula used to discover the iron deficit in mg is: Iron deficit (mg) = Patient weight in kg x (14 – Hb in g/dL) x 2.145. The volume of product required to replenish iron stores is: Volume of product (mL) = Iron deficit in mg / C in mg/mL. Where C is the concentration of the iron product: ■ 50 mg/mL for Iron dextran;

How do you calculate iron deficiency?

The iron deficit estimation is based on the Ganzoni formula: Total iron deficit (mg) = Weight in kg x (Target Hb – Actual Hb in g/dL) x 2.4 + Iron stores. Most adults require a cumulative dose of elemental iron of at least 1 g.

How do you calculate iron deficit?

The total iron deficit is calculated using the Ganzoni formula: Total Iron Deficit = Weight x (Target Hb in g/dL – Actual Hb in g/dL) x 2.4 + Iron Stores Note: 500 if W > 35kg 15 mg/kg if W < 35kg Recommended value : 500mg.