What is Phagocytized by keratinocytes?
Keratinocytes phagocytize chunks of melanin produced by melanocytes and incorporate the melanin in the tops of their cells. Merkel Cells – Hemispherical cells at the boundary between the epidermis and the dermis.
How do melanocytes and keratinocytes work together to protect the skin from UV damage?
Melanocytes and keratinocytes work together in protecting the skin from UV damage because the role of the keratinocytes is to: accumulate the melanin granules on their superficial portion, forming a pigment that protects DNA from UV radiation.
What is hemoglobin in skin?
When a person appears pale, it may be because there is not enough oxygen-rich hemoglobin near the skin’s surface. Hemoglobin is a protein in red blood cells that transports oxygen, and several conditions can reduce hemoglobin levels. Paleness is different from low levels of pigment in the skin.
Which of the following is most important in determining skin coloration keratin Haemoglobin melanin carotene?
Melanin is responsible for skin color, carotene can provide some protection against the sun.
What does Phagocytized mean?
to envelop and destroy bacteria and other foreign material; phagocytize.
Which layer of the integument contains rapidly dividing keratinocytes?
stratum germinativum
The deepest layer of the epidermis is the stratum germinativum. Here keratinocytes are actively dividing (and producing keratin and previtamin D3). Melanocytes also inhabit this layer and produce melanin.
What is the relationship between keratinocytes and melanocytes?
Keratinocytes are the most abundant cells in the epidermis. They are responsible for the production of keratin that serves as the mechanical barrier for damage. Melanocytes are responsible for the production of melanin that provides the color to the skin.
What is the pigment that protects the DNA of keratinocytes from mutations induced by UV radiation?
Melanocytes, a neural crest cell derivative, produce pigment to protect keratinocytes from ultraviolet radiation (UVR).
How do keratinocytes contribute to skin color?
Exposure to the UV rays of the sun or a tanning salon causes melanin to be manufactured and built up in keratinocytes, as sun exposure stimulates keratinocytes to secrete chemicals that stimulate melanocytes. The accumulation of melanin in keratinocytes results in the darkening of the skin, or a tan.
How does hemoglobin affect skin tone?
Hemoglobin is the iron-containing protein pigment of our blood cells. A lack of oxygen saturation imparts a paler, grayer, or bluer color to the skin. Skin may also become paler as a result of anemia (a reduced number of hemoglobin and/or red blood cells), low blood pressure, or poor circulation of blood.
Do keratinocytes produce keratin?
Keratinocytes. Keratinocytes do much more than produce keratin, surface lipids, and intercellular substances (see Chapter 1). They are intimately associated with Langerhans’ cells and play a major role in the SIS.