What are the symptoms of blastoma?

What are the symptoms of blastoma?

Symptoms include:

• abdominal swelling or a lump felt in the abdomen.
• fever.
• blood in the urine.
• change in the urine’s color.
• loss of appetite.
• high blood pressure.
• abdominal pain.
• shortness of breath.

What are the causes of PPB?

Because PPB is so rare, doctors often believe at first examination that the symptoms are caused by a common childhood illness. There are 2 common sets of symptoms that may indicate PPB: Sudden, stressful breathing may be caused by air escaping from the lung cysts into the chest cavity.

What is pulmonary blastoma?

Pulmonary blastoma is an unusual lung malignancy, constituting about 0.5% of all lung tumors[1-4]. Its histology resembles lung fetal tissue and can express both epithelial and mesenchymal features. Despite its assumed embryonal origin, the tumor predominantly affects adults[3].

Are neuroblastomas painful?

Spread to bones: Neuroblastoma often spreads to bones. A child who can talk may complain of bone pain. The pain may be so bad that the child limps or refuses to walk. If it spreads to the bones in the spine, tumors can press on the spinal cord and cause weakness, numbness, or paralysis in the arms or legs.

Where do neuroblastomas occur?

Neuroblastomas are cancers that start in early nerve cells (called neuroblasts) of the sympathetic nervous system, so they can be found anywhere along this system. Most neuroblastomas begin in the abdomen, either in an adrenal gland or in sympathetic nerve ganglia.

What is Pleuropulmonary disease?

Summary. Pleuropulmonary blastoma (PPB) is a rare childhood cancer occurring in the chest, specifically in the lungs or in the coverings of the lungs called “pleura”.

What organs does rhabdomyosarcoma affect?

Rhabdomyosarcoma is a rare type of cancer that affects muscle tissue, mostly in children and adolescents. It can occur anywhere in the body, but usually the head and neck, arms and legs, and urinary and reproductive organs.

How does neuroblastoma affect the eyes?

Eyes that bulge out and dark circles under the eyes, if the cancer has spread behind the eyes. Changes in the eyes, such as black eyes, a droopy eyelid, a pupil that is constricted, vision problems, or changes in the color of the iris.

What are the different types of pleuropulmonary blastoma?

General Discussion. Summary. Pleuropulmonary blastoma (PPB) is a rare childhood cancer occurring in the chest, specifically in the lungs or in the coverings of the lungs called “pleura”. Three subtypes of PPB exist and are called Type I, Type II, and Type III PPB.

How is pleuropulmonary blastoma ( PPB ) treated?

Treatment for Type I consists of surgery and possibly chemotherapy. Treatment for Types II and III PPB consists of surgery and chemotherapy and possibly radiation therapy. At present, about 50-70% of children with Types II and III PPB are cured.

How is pleuropulmonary blastoma related to Wilms tumor?

Pleuropulmonary blastoma is associated with PPB family tumor and dysplasia syndrome in 33% of cases. Many of these patients have a mutation of the DICER1 gene. In 10% of cases, patients with PPB may also present with multilocular cystic nephroma, and, very rarely, Wilms tumor 7-9.

What kind of malignancy is a Blastoma in a child?

Pleuropulmonary blastomas (PPB) are a rare, variably aggressive, childhood primary intrathoracic malignancy. In up to 25% of cases, the mass can be extrapulmonary with attachment to the parietal pleura .