How do you calculate aminophylline infusion?

How do you calculate aminophylline infusion?

aminophylline into 500 ml of normal saline solution. So, 1 ml will have 1/500 × 200 = 0.5 mg of aminophylline. So, 30 mg will be present in 30/0.5 × 1 = 60 ml, which is to be administered in 1 h. So, the rate of aminophylline administration will be 16-20 drops/min.

How do you administer pantoprazole iv?

PROTONIX I.V. for Injection should be administered intravenously over a period of approximately 15 minutes at a rate of approximately 7 mL/min. PROTONIX I.V. for Injection should be reconstituted with 10 mL of 0.9% Sodium Chloride Injection, USP, per vial to a final concentration of approximately 4 mg/mL.

How do you infuse aminophylline?

Add 500mg to 500mL or 250mg to 250mL of a compatible infusion fluid (1mg/mL). Administer using a rate controlled infusion pump. Aminophylline infusions should be continued for at least 24 hours with review by medical staff at agreed intervals, and may be continued for a further 24-48 hours.

How do you give pantoprazole drip?

Pantoprazole 80 mg (2 vials) IV: Mix medication in 20 mL 0.9% NS in a syringe and give IV push or via syringe infuser or in a 50 mL minibag. Solution is stable for 21 hours at room temperature. One 100 mL bag will last 5 hours.

What is aminophylline infusion?

Aminophylline Injection is indicated for relief of bronchospasm associated with asthma and in chronic obstructive pulmonary disease. Maintenance therapy can be administered via larger volume infusion solutions, rate-regulated to deliver the required amount of drug each hour.

Why is aminophylline injection given slowly?

Intravenous Aminophylline must be administered very slowly to prevent dangerous central nervous system and cardiovascular side-effects due to direct stimulating effect of Aminophylline.

How do you dilute IV pantoprazole?

PROTONIX I.V. for Injection should be reconstituted with 10 mL of 0.9% Sodium Chloride Injection, USP, and further diluted (admixed) with 100 mL of 5% Dextrose Injection, USP, 0.9% Sodium Chloride Injection, USP, or Lactated Ringer’s Injection, USP, to a final concentration of approximately 0.4 mg/mL.

How is pantoprazole infusion calculated?

PANTOPRAZOLE (Pantoloc)

1. Bolus: 40-80 mg in 100 mL sodium chloride 0.9%, dextrose 5% or Ringer’s Lacate infused over 15-60 minutes.
2. Infusion: 40 mg in 100 mL sodium chloride 0.9%, dextrose 5% or Ringer’s Lacate. bag stable only for 6 hours; do not prepare large size bag.

How do you dilute IV aminophylline?

Dilute 1000mg aminophylline in 1000ml sodium chloride 0.9% or 1000ml glucose 5%, to make a concentration of 1mg per 1mL, and administer as a continuous intravenous infusion. Maintenance doses should be administered immediately after the loading dose. Expiry: Once reconstituted, aminophylline has a 24 hour expiry.

Why is IV aminophylline given slowly?

Does aminophylline increase heart rate?

Aminophylline competitively antagonizes the cardiac actions of adenosine at the cell surface receptors. Thus, it increases heart rate and contractility.

How is Pantoprazole infusion calculated?

How to convert intravenous aminophylline to twice a day?

This dose is then divided by the daily frequency of oral theophylline administration. A simplified approach for this conversion is to multiply the mg/hour of intravenous aminophylline that the patient is receiving by ten to yield the dose of sustained-release theophylline to be administered every 12 hours.

When do you stop intravenous aminophylline infusions?

It is recommended that dose reduction begin in the morning, aiming to stop the infusion by mid to late afternoon. This allows oral theophyllines (if appropriate) to be given that evening. completely, and to confirm that oral theophyllines are to be started.

How much theophylline can be given in one infusion?

In patients with cor pulmonale, cardiac decompensation, or liver dysfunction, or in those taking drugs that markedly reduce theophylline clearance (e.g., cimetidine), the initial theophylline infusion rate should not exceed 17 mg/hr (21 mg/hr as aminophylline) unless serum concentrations can be monitored at 24-hour intervals.

What should be the target concentration of aminophylline?

* To achieve a target concentration of 10 mcg/mL Aminophylline=theophylline/0.8. Use ideal body weight for obese patients. † Lower initial dosage may be required for patients receiving other drugs that decrease theophylline clearance (e.g., cimetidine).