What is atypical lymphocytic infiltrate?
Atypical lymphoid infiltrates occurring in the setting of connective-tissue disease (CTD) comprise malignant neoplasms of B-cell or T-cell phenotypes and various reactive lymphoid hyperplasias, such as myoepithelial sialadenitis, lymphocytic thyroiditis, and lymphocytic interstitial pneumonitis.
What is a lymphocytic infiltrate?
Lymphocytic infiltrate of Jessner is a rare skin condition that may be characterized by non-cancerous (benign) buildup of white blood cells, which present as lesions or lumps on the skin.
What causes lymphocytic infiltration?
Lymphocytic infiltration is mostly due to cytotoxic T-lymphocyte cells that cause anterior pituicyte destruction and fibrotic replacement with fibrosis.
What is atypical lymphoid cell?
Atypical lymphocytes refer to reactive lymphocytes in viral, parasitic or mycotic infection. They vary in size from near-normal to very large. They may be oval or round with regular outline, or scalloped to assume the contour of juxtaposed erythrocytes.
How is lymphocytic infiltrate treated?
Lymphocytic infiltrate of Jessner may require no treatment (since it can resolve spontaneously), but some patients benefit from cosmetic camouflage, photoprotection, surgery to remove small lesions, use of steroids orally or topically, antimalarial medications such as hydroxychloroquine, cryotherapy, methotrexate.
Is lymphocytic infiltrate benign?
Jessner’s lymphocytic infiltrate (JLI), also called benign lymphocytic infiltration of the skin, is a rare, benign dermatosis with a self-limiting course and an excellent prognosis. It typically presents as erythematous papules and plaques primarily located on the face, neck, or upper back.
What does atypical mean in medical terms?
abnormal
Atypical (ay-TIP-ih-cul) is a medical word for “abnormal.” Doctors may use this word to describe cells or body tissues that look unusual under a microscope. They might also say your case is atypical if you don’t have the usual symptoms of your type of cancer.
What are the two major types of lymphocytes?
Lymphocytes are cells that circulate in your blood that are part of the immune system. There are two main types lymphocytes: T cells and B cells. B cells produce antibody molecules that can latch on and destroy invading viruses or bacteria.
What do lymphoblasts do?
Lymphoblast also refers to an immature cell that can develop into a mature lymphocyte. Blood cell development. A blood stem cell goes through several steps to become a red blood cell, platelet, or white blood cell.
What is atypical squamous proliferation?
Atypical squamous cells are typically discovered during a routine Pap smear. This is a gynecological test where a doctor collects and examines cells from the cervix to determine if they are healthy. If any cells appear abnormal, this is referred to as dysplasia, which may be a precursor to cancer.
What does lymphocytic infiltration mean?
Lymphocytic Infiltrate. A morphologic finding referring to the presence of a cellular infiltrate that is composed of non-neoplastic or neoplastic lymphocytes in a tissue sample.
What is lymphohistiocytic infiltrate?
Lymphohistiocytosis is “a widespread infiltrate of non-malignant lymphocytes and macrophages, involving principally the liver, spleen and central nervous system and associated with a severe lymphoid atrophy.”.