What is undetectable HBV viral load?
Inactive Carrier State: Most people transition into the inactive hepatitis B phase, which is characterized by undetectable or low viral loads (less than 2,000 IU/mL) and improvement in liver inflammation and fibrosis. Adults in this phase will also typically have normal ALT levels and minimal inflammation.
What is high viral load in hepatitis B?
A viral load of > 10 000 copies/mL (2000 IU/mL) is a strong risk predictor of HCC, independent of HBeAg status, ALT level and liver cirrhosis[10,21,22].
What is HBV Quantitative?
A quantitative result expressed in IU/mL and log IU/mL indicates the degree of active HBV viral replication in the patient. Monitoring HBV DNA levels over time is important for assessing disease progression or monitoring a patient’s response to anti-HBV therapy.
What does HBV DNA detected mean?
The presence of HBV DNA in serum is a reliable marker of active HBV replication. HBV DNA levels are detectable by 30 days following infection, generally reach a peak at the time of acute hepatitis, and gradually decrease and disappear when the infection resolves spontaneously.
What is a good viral load count?
What the Results Mean. A high viral load is generally considered about 100,000 copies, but you could have 1 million or more. The virus is at work making copies of itself, and the disease may progress quickly. A lower HIV viral load is below 10,000 copies.
What is HBV Quantitative real time PCR?
The HBV Quantitative (Viral load) – Real time PCR test helps to assess the progression of the Hepatitis B virus disease. It also helps to monitor the efficacy of treatment undergoing for the Hepatitis B virus. This test uses Real Time PCR method.
What is the normal level of HBV DNA?
An undetectable viral load (which means fewer HBV DNA than a lab’s equipment can identify) generally is lower than about 300 copies/mL. Moderate levels of HBV DNA begin at about 10,000 to copies/mL.
How is the viral load of HBV measured?
The HBV DNA test is performed on a blood sample using a Polymerase Chain Reaction (PCR) technique that rapidly generates HBV DNA fragments so they can be measured. Today, viral load is usually measured using international units per milliliter (IU/mL).
What is the quantification range of hbvqn?
Interpretation The quantification range of this assay is 10 to 1,000,000,000 IU/mL (1.00 log to 9.00 log IU/mL). An “Undetected” result indicates that hepatitis B virus (HBV) DNA was not detected in the serum specimen.
When to follow up with HBV DNA test?
A result of “<10 IU/mL (<1.00 log IU/mL)” indicates that HBV DNA is detected, but the HBV DNA level present cannot be quantified accurately below this lower limit of quantification of this assay. When clinically indicated, follow-up testing with this assay is recommended in 1 to 2 months.