How do you identify Capnocytophaga?
Laboratory Identification of Capnocytophaga Capnocytophaga species are fastidious, slow-growing, Gram-negative bacteria. Blood samples are usually used for culture identification.
Is Capnocytophaga normal flora?
haemolytica, and C. granulosa (“human” Capnocytophaga) are normal flora of the gingival sulci of humans. They are closely related to both Fusobacterium and Bacteroides/Prevotella spp.
How common is Capnocytophaga?
Recent estimates using PCR techniques to amplify bacterial DNA are that Capnocytophaga canimorsus is in the mouths of 74% of dogs and 57% of cats. Although the bacteria are common in household pets’ mouths, overwhelming infections with Capnocytophaga canimorsus or “dog bite septicemia” are rare.
Should I worry about Capnocytophaga?
Should You Worry About Capnocytophaga? Despite the dire mortality rate, capnocytophaga is extremely rare. It also isn’t new. These bacteria have been around for a long time, and while recent cases may have drawn attention to it, that doesn’t mean you need to panic.
Is Capnocytophaga anaerobic?
Capnocytophaga species are facultative anaerobic, capnophilic, fusiform, gram-negative bacilli exhibiting gliding motility; they are normal inhabitants of the oropharyngeal flora [1].
Which antibiotics treat Capnocytophaga?
In general, many antibiotics, including penicillins, clindamycin, macrolides, and quinolones, are effective in treating Capnocytophaga infections (6, 10, 11, 21).
What is C gingivalis?
Capnocytophaga is a genus of Gram-negative bacteria. Normally found in the oropharyngeal tract of mammals, they are involved in the pathogenesis of some animal bite wounds and periodontal diseases.
Is Capnocytophaga Canimorsus oxidase positive?
canimorsus include positive test results for oxidase, catalase, arginine dihydrolase, and o-nitrophenyl-β-d-galactopyranoside and negative reactions for urease, nitrates, and indole.
Can amoxicillin treat Capnocytophaga?
In view of the increasing evidence of beta-lactamase producing strains of Capnocytophaga spp., it is prudent to treat patients with serious infections with amoxicillin combined with clavulanic acide (or other beta-lactams + beta-lactamase-inhibitor combinations or imipenem in case of severe infections (58, 63).
Does everyone have P gingivalis?
gingivalis is a pathogen, then it would be expected to be detected in most subjects with disease and rarely detected in subjects who are periodontally healthy. However, in most previous studies, P. gingivalis has not been detected in the majority of subjects with disease.
Are there any cases of Capnocytophaga in humans?
Capnocytophaga species cause rare but severe infection in humans. The incidence of infection due to C. canimorsus in the general population is low. National surveillance for Capnocytophaga species is not performed in the United States; a national survey in the Netherlands noted 0.67 cases per million per year [1].
Is the Capnocytophaga part of the oral microflora?
Capnocytophaga species constitute part of the normal oral microflora of humans and animals ( 61 ), and are often considered as opportunistic pathogens, that was confirmed by recent studies of microbial profiles using the human oral microbe identification microarray ( 23 , 54 , 128 , 131 ).
How often is Capnocytophaga canimorsus found in the US?
The incidence of infection due to C. canimorsus in the general population is low. National surveillance for Capnocytophaga species is not performed in the United States; a national survey in the Netherlands noted 0.67 cases per million per year [ 1 ].
How long does it take a Capnocytophaga to grow?
Capnocytophaga Species Capnocytophaga species are filamentous, thin, gram-negative rods with a tapered end (fusiform) that are capnophilic, requiring increased levels of carbon dioxide for ideal growth that often takes 48 hours on blood agar plates.