What is the drug ZEMPLAR used for?
Paricalcitol is used to treat and prevent high levels of a certain natural substance made by the body (parathyroid hormone) in patients with long-term kidney disease.
How is ZEMPLAR given?
Administer ZEMPLAR intravenously through a hemodialysis vascular access port at any time during dialysis. ZEMPLAR may be administered intravenously if an access port is unavailable. Inspect ZEMPLAR visually prior to administration; the solution should appear clear and colorless.
How do you give a ZEMPLAR IV?
This medication is given by injection into a vein during dialysis, usually by a health care professional. It is given as directed by your doctor, usually 3 times a week (every other day). The dosage is based on your condition, weight, laboratory tests, and response to treatment.
When do you hold the ZEMPLAR?
Administer ZEMPLAR capsules orally once daily or three times a week [see Clinical Studies (14.1)]. When dosing three times weekly, do not administer more frequently than every other day.
Is Ergocalciferol a steroid?
Mechanism. Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light (UV-B or UV-C) on ergosterol, a form of provitamin D2.
What class of drug is zemplar?
Zemplar Overview Zemplar is a prescription medication used to treat high levels of the parathyroid hormone (PTH) in those with chronic kidney disease. Zemplar belongs to a group of drugs called vitamin D analogs, which help regulate PTH levels and increase calcium in your body.
What is secondary parathyroid disease?
Secondary hyperparathyroidism is a condition in which a disease outside of the parathyroid glands causes all of the parathyroid glands to become enlarged and hyperactive. The most common causes of secondary hyperparathyroidism are kidney failure and vitamin D deficiency.
When do you give paricalcitol?
Take paricalcitol capsules at least 1 hour before or 4 to 6 hours after taking cholestyramine or mineral oil.
Is zemplar a vitamin D?
ZEMPLAR Capsules are an active form of vitamin D used to prevent and treat secondary hyperparathyroidism (increased parathyroid hormone levels) in adults and children 10 years of age and older with Stage 3 or Stage 4 chronic kidney disease and in Stage 5 patients on dialysis.
Why do people take ergocalciferol?
Calciferol (ergocalciferol) is vitamin D2 used to treat hypoparathyroidism (decreased functioning of the parathyroid glands), and is also used to treat rickets (softening of the bones caused by vitamin D deficiency) or low levels of phosphate in the blood (hypophosphatemia).
Can ergocalciferol cause kidney stones?
Oral supplementation with cholecalciferol has been associated with increased risk of stones when administered together with calcium;6 however, administration of ergocalciferol in stone formers with vitamin D deficiency did not cause a significant rise in mean urinary calcium excretion.
Who makes zemplar?
AbbVie
Paricalcitol: Zemplar | AbbVie.
What is the active ingredient in Zemplar injection?
Paricalcitol, USP, the active ingredient in Zemplar Injection, is a synthetically manufactured analog of calcitriol, the metabolically active form of vitamin D indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 5.
When to take Zemplar capsules for kidney disease?
ZEMPLAR Capsules are an active form of vitamin D used to prevent and treat secondary hyperparathyroidism (increased parathyroid hormone levels) in adults and children 10 years of age and older with Stage 3 or Stage 4 chronic kidney disease and in Stage 5 patients on dialysis.
What kind of medicines can you take with Zemplar?
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Zemplar, especially: 1 conivaptan; 2 digoxin; 3 nefazodone; 4 an antibiotic – clarithromycin, telithromycin; 5 antifungal medicine – itraconazole, ketoconazole, posaconazole, voriconazole; or. 6 (1 more items)
How old do you have to be to take Zemplar?
ZEMPLAR is indicated for the prevention and treatment of secondary hyperparathyroidism in patients 5 years of age and older with chronic kidney disease (CKD) on dialysis.