What is SKOV3 cell line?

What is SKOV3 cell line?

3; SKOV3; Skov3 and SKO3) is an ovarian cancer cell line derived from the ascites of a 64-year-old Caucasian female with an ovarian serous cystadenocarcinoma. The SK-OV-3 cell line is also hypodiploid, with a modal number of chromosomes of 43 (range 42-45), occurring in 63.3% of cells.

What is ovcar3?

NIH:OVCAR-3 is an appropriate model system in which to study drug resistance in ovarian cancer, and the presence of hormone receptors should be useful for the evaluation of hormonal therapy.

What are ovarian cancer cell lines?

Together, the papillary serous, clear cell, endometrioid and mucinous subtypes account for >90% of ovarian adenocarcinomas; accordingly this panel of cell lines is broadly representative of ovarian cancer.

What is the survival rate of stage 4 ovarian cancer?

Most women diagnosed with Stage 4 ovarian cancer have a five-year survival rate of approximately 17%. Survival rates are often based on studies of large numbers of people, but they can’t predict what will happen in any particular person’s case.

What is ovarian serous Cystadenocarcinoma?

Ovarian serous cystadenocarcinoma is the malignant form of ovarian serous tumor, the most common type of ovarian epithelial tumor. It is the most common type of ovarian malignancy.

What is the cell line of the human cervical carcinoma?

HeLa cells (human cervical cancer cell line) are grown in monolayer cultures at 37° and 5% CO2 in Ham’s F10 medium supplemented with 10% (v/v) calf serum (GIBCO, Grand Island, NY), penicillin (100 U/ml), and streptomycin (100 μg/ml).

Where does ovarian cancer spread first?

Where does ovarian cancer spread first? There is no single trajectory for where ovarian cancer will spread; however, if not caught in early stages, most cases of ovarian cancer will follow a similar path: from the pelvis, to more distant parts of the abdomen and peritoneal cavity, to the lymph nodes, and the liver.

What are C6 cells?

C6 cell line was developed in adult Wistar-Furth rats in the late 1960s after the rats were repetitively exposed to N-Nitroso-N-methylurea5. This glioma cell line is composed of pleomorphic cells with variably shaped nuclei.