What is Krukenberg spindle?
Krukenberg’s spindle represents melanin pigment forming a vertical line on the posterior central cornea in contrast to other melanin pigment depositions that tend to be more circular or diffuse in distribution.
What are eye spindles?
Krukenberg’s spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonular fibrils that are deposited as a result of the currents of the aqueous humor.
Does pigment dispersion syndrome cause glaucoma?
How Does Pigment Dispersion Syndrome Cause Glaucoma? Pigment dispersion syndrome can lead to permanent damage to the drain and elevated eye pressure. Over time, the elevated eye pressure can damage the optic nerve, causing pigmentary glaucoma. Untreated glaucoma can lead to vision loss and eventually blindness.
What causes pigment dispersion syndrome?
Pigment dispersion syndrome is a condition that happens when pigment rubs off of the back of the iris of the eye when the fibers supporting the lens rub against it. This pigment is deposited in the trabecular meshwork of the eye, where the fluid drains out.
Does high eye pressure always mean glaucoma?
High intraocular pressure doesn’t always lead directly to glaucoma. Along with other things, high IOP is considered an important risk factor for the disease.
What causes iris Transillumination?
Known causes of acquired iris atrophy with or without transillumination of the iris include herpetic iridocyclitis, pigment dispersion syndrome (PDS), pseudoexfoliation syndrome, Fuchs uveitis syndrome, Vogt-Koyanagi-Harada disease, trauma, and acute angle-closure glaucoma.
How is Krukenberg’s spindle formed in the cornea?
Krukenberg’s spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor.
Which is the correct description of Krukenberg’s spindle syndrome?
Pigment dispersion syndrome is characterized by accumulation of pigment on the posterior surface of the central cornea in a vertical, spindle-shaped pattern (Krukenberg’s spindle) (Fig. 30-13). Pigment granules may also be deposited on the anterior surface of the lens and on the iris, leading to heterochromia.
Why does my krukenbergs spindle keep falling off?
Krukenbergs spindle is an early sign of Pigment Dispersion Syndrome (PDS) which is generally believed to be a genetic condition, but this isn’t clear. With PDS small flakes of the colored part of your eye fall off and wander around in the liquid part of the eye, similar to what are commonly called floaters.
Can a flat cornea cause burping and blinking?
A flat cornea might be more likely to result in burping of aqueous humor from the posterior chamber to the anterior chamber with blinking, resulting in increased iridozonular contact 29). Family history. Direct examination of a small set of family members of pigment dispersion syndrome patients showed that disease was present in 2/19 (12%) 30).