What if a karyotype has XXY?
Usually, a female baby has 2 X chromosomes (XX) and a male has 1 X and 1 Y (XY). But in Klinefelter syndrome, a boy is born with an extra copy of the X chromosome (XXY). The X chromosome is not a “female” chromosome and is present in everyone. The presence of a Y chromosome denotes male sex.
Is 47 Xyy a normal karyotype?
XYY syndrome is a rare chromosomal disorder caused by the presence of an extra Y chromosome. Normally, males have 46 chromosomes including one X and one Y chromosome. Males with XYY syndrome have 47 chromosomes, two of which are Y chromosomes.
Does XXY mean Down syndrome?
With the discovery in 1956 that the correct chromosome number in humans is 46, the new area of clinical cytogenetic began its rapid growth. Several major chromosomal syndromes with altered numbers of chromosomes were reported, such as Down syndrome (trisomy 21), Turner syndrome (45,X) and Klinefelter syndrome (47,XXY).
What is Klinefelter syndrome karyotype 47 XXY?
Klinefelter Syndrome (47, XXY) is a chromosomal variation in males in which one extra X chromosome is present, resulting in a 47,XXY karyotype. The extra X chromosome typically affects physical, neurodevelopmental, behavioral, and neurocognitive functioning.
What causes XXY syndrome?
Males have an X and a Y sex chromosome (XY). Klinefelter syndrome can be caused by: One extra copy of the X chromosome in each cell (XXY), the most common cause. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms.
What would happen if humans had 47 chromosomes?
47,XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Affected boys can have delayed development of motor skills (such as sitting and walking) or weak muscle tone (hypotonia).
Is Xyy a disability?
Some boys with 47, XYY syndrome may have difficulty in certain subjects in school such as reading and writing. However, boys with this syndrome do not typically have intellectual disability . Other signs and symptoms of 47, XYY syndrome may include asthma, dental problems, and acne.
What condition is modeled by the expression 47 XXY?
How do you describe a karyotype?
A karyotype is an image which depicts an organism’s chromosomes. The term is also used to refer more generally to the complement of chromosomes found in a healthy representative of a species.
What is the difference between normal and abnormal karyotype?
If a karyotype shows a usual number and structure of chromosome set, it is known as a normal karyotype. Abnormal karyotype shows an unusual number or structurally malformed chromosomes in the karyotype. This is the key difference between normal and abnormal karyotype.
How common is XYY syndrome?
XYY syndrome is listed as a ” rare disease ” by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that XYY syndrome, or a subtype of XYY syndrome, affects less than 200,000 people in the US population.
What is a karyotype result?
Karyotype is a test to identify and evaluate the size, shape, and number of chromosomes in a sample of body cells. Results of a karyotype test are usually available within 1 to 2 weeks. There are 46 chromosomes that can be grouped as 22 matching pairs and 1 pair of sex chromosomes (XX for a female and XY for a male).