Is Plasil safe during pregnancy?
Risk Summary: Malformative risk with use of this drug in pregnant women is unlikely. Comments: -Use during the first and third trimesters should be avoided when possible. -Monitoring for extrapyramidal syndrome and methemoglobinemia is recommended for neonates exposed during the third trimester and/or delivery.
What are the side effects of metoclopramide in pregnancy?
There have been some reports of menstrual problems and galactorrhea (milk production that is not related to breastfeeding) among women who have taken metoclopramide. Women who have these side effects might have a harder time becoming pregnant.
Which anti emetic is safe in pregnancy?
| Table 1: Antiemetics suitable for use in pregnancy (in order of preference)3,4,10 | |
|---|---|
| Medication | Dose |
| Cyclizine | 50 mg three times daily |
| Promethazine | 25 mg at bedtime, increased to maximum 100 mg daily in divided doses |
| Ondansetron (hyperemesis gravidarum) | 4 – 8 mg two to three times daily |
Can you take promethazine while pregnant?
Pregnancy and breastfeeding Promethazine can be used in pregnancy. There is no good evidence that it is harmful to your baby, but it can have side effects such as drowsiness. For the treatment of hay fever your doctor or pharmacist may recommend a non-drowsy antihistamine (loratadine).
Is metoclopramide safe for first trimester?
In this large, population-based cohort, we found no significant association between metoclopramide treatment in the first trimester and adverse outcomes for the fetus, including congenital malformations, perinatal death, low birth weight, and low Apgar scores.
Is granisetron safe in pregnancy?
Objective: Current guidelines suggest that granisetron is an optional treatment for nausea and vomiting in pregnancy (NVP) despite lack of evidence to support fetal safety.
Is promethazine safe during pregnancy?
Pharmacologic Therapy for Nausea and Vomiting of Pregnancy
| Medication | Pregnancy category |
|---|---|
| Prochlorperazine (Compazine) | C |
| Promethazine (Phenergan) | C |
| Trimethobenzamide (Tigan) | C |
| Ondansetron (Zofran) | B |
Is it safe to take promethazine while pregnant?
Is it safe to take clindamycin during pregnancy?
Clindamycin (Cleocin, Clinda-Derm, Clindagel) Certain other antibiotics are believed to pose risks during pregnancy. For example, tetracyclines can affect bone development and discolor a developing baby’s teeth. Tetracyclines aren’t recommended for use after the fifth week of pregnancy.
When is it safe to take sulfonamides during pregnancy?
Tetracyclines aren’t recommended for use after the fifth week of pregnancy. Sulfonamides might pose a small risk of heart conditions, cleft lip or palate, and jaundice. Sulfonamides are generally avoided during the first trimester of pregnancy and near the time of delivery.
What are the risks of taking salicylates during pregnancy?
Salicylates have been associated with increased perinatal mortality, neonatal hemorrhage, decreased birth weight, prolonged gestation and labor, and possible birth defects. 5 However, one study 7 found that low-dose aspirin is not associated with an increased risk of abruptio placentae or increased rates of perinatal mortality.
What are the risks of taking metoclopramide during pregnancy?
Metoclopramide in pregnancy and risk of major congenital malformations and fetal death Metoclopramide use in pregnancy was not associated with increased risk of major congenital malformations overall, any of the 20 individual malformation categories assessed, spontaneous abortion, or stillbirth.