How many units is NovoSeven?

How many units is NovoSeven?

NovoSeven 8 mg (400 KIU) NovoSeven is presented as powder and solvent for solution for injection containing 8 mg eptacog alfa (activated) per vial (corresponds to 400 KIU/vial). 1 KIU equals 1,000 IU (International Units).

What is the difference between NovoSeven and NovoSeven RT?

The new NovoSeven RT provides the same safety and efficacy as the original NovoSeven(R)-but it can be transported and administered quickly.” NovoSeven RT has been manufactured to be room temperature stable (from 36 degrees F to 77 degrees F outside a refrigerator).

What does RT stand for in NovoSeven RT?

What does this rFVIIa treatment mean for you? NovoSeven® RT means speed, effectiveness and portability. It’s a recombinant bypassing agent that you infuse on-demand, and has a long history of helping people control their bleeds. Take a Closer Look.

How fast does NovoSeven work?

Fast bleed control. Helps control joint bleeds in as few as 5 hours with a median of 2 doses.

What is NovoSeven used for?

This medication is used to treat and prevent bleeding in people with certain conditions (such as hemophilia type A or B, low levels of factor VII, Glanzmann’s thrombasthenia).

How expensive is NovoSeven?

The cost for NovoSeven RT intravenous powder for injection (1000 mcg (1 mg)) is around $2,515 for a supply of 1000 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

Is NovoSeven activated?

Activation. NovoSeven® RT binds directly to activated platelets, activating FX to produce FXa. FXa complexes with other factors to convert prothrombin to thrombin.

When should I take NovoSeven?

Surgical intervention (NovoSeven RT)

1. Indicated for prevention of bleeding in surgical interventions or invasive procedures in hemophilia A or B with inhibitors and in acquired hemophilia.
2. 90 mcg/kg IV immediately before intervention, THEN q2hr for surgery duration.

When do you use NovoSeven?

INDICATIONS AND USAGE

1. NovoSeven is indicated for:
2. Factor IX and in patients with acquired hemophilia.
3. patients with inhibitors to Factor VIII or Factor IX and in patients with acquired hemophilia.
4. • prevention of bleeding in surgical interventions or invasive procedures in patients with.

What is NovoSeven made from?

NovoSeven is a novel product and contains activated recombinant DNA human coagulation factor VII (rFVIIa). The recombinant molecule is produced in baby hamster kidney (BHK) cells. Recombinant FVIIa is almost identical to human plasma FVIIa except for a difference in glycosylation.

What should the room temp be for NovoSeven RT?

2. Bring NovoSeven RT (white, lyophilized powder) and the specified volume of histidine (diluent) to room temperature, but not above 37°C (98.6° F). The specified volume of diluent corresponding to the amount of NovoSeven RT is as follows:

How much histidine is in a vial of NovoSeven RT?

Bring NovoSeven RT (white, lyophilized powder) and the specified volume of histidine (diluent) to room temperature, but not above 37°C (98.6° F). The specified volume of diluent corresponding to the amount of NovoSeven RT is as follows: 1 mg (1000 micrograms) vial + 1.1 mL Histidine diluent 2 mg (2000 micrograms) vial + 2.1 mL Histidine diluent

Are there any side effects to taking NovoSeven RT?

Arterial and venous thrombotic and thromboembolic events following administration of NovoSeven have been reported during postmarketing surveillance. Clinical studies have shown an increased risk of arterial thromboembolic adverse events with NovoSeven RT when administered outside the current approved indications.

How to inject NovoSeven RT with a syringe needle?

6. Insert the syringe needle containing the diluent into the NovoSeven RT vial through the center of the rubber stopper, aiming the needle against the side so that the stream of liquid runs down the vial wall (the NovoSeven RT vial does not contain a vacuum). Do not inject the diluent directly on the NovoSeven RT powder.