Can medications cause skin darkening?
The main drugs implicated in causing skin pigmentation are nonsteroidal anti-inflammatory drugs, antimalarials, amiodarone, cytotoxic drugs, tetracyclines, heavy metals and psychotropic drugs.
What medications can cause pigmentation?
Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs (NSAIDs), phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals.
Which medications cause melasma?
Drugs such as steroids, cosmetics, and photosensitizing agents are known to cause melasma. We report here a case of an adult male with obsessive-compulsive disorder, receiving clomipramine, who developed melasma. Chemicals (cosmetics), steroids, and photosensitizing drugs may produce melasma.
What is drug-induced pigmentation?
Drug-induced pigmentation is a form of abnormal skin pigmentation that is caused by drugs through several different mechanisms. Several drugs have associations with pigmentation, including cytotoxic agents, analgesics, anticoagulants, antimicrobials, antiretrovirals, metals, and antiarrhythmic, etc.
Can medication change your skin color?
Drug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin.
How does medication affect the skin?
Certain medications can cause your skin to react when you exposed it to sunlight. These reactions are called drug-induced photosensitivity reactions. They can arise from medications taken by mouth or applied to the skin.
Which antibiotics cause hyperpigmentation?
[5] The drugs that can cause hyperpigmentation, which are used frequently in patients with kidney disease are hydroxychloroquine, ketoconazole, and tetracycline antibiotics.
Can medications cause melasma?
Antiseizure medications: Drugs that prevent you from having seizures may be a cause of melasma. An example of an antiseizure medication is Clobazam (Onfi®). Contraceptive therapy (birth control): Melasma has been observed in individuals who use oral contraceptive pills that contain estrogen and progesterone.
Does metformin cause melasma?
When melanocytes were treated with metformin, basal level of total melanin (eumelanin and pheomelanin) were reduced significantly. Also metformin blocked forskolin and alpha melanocyte-stimulating hormone which increase the levels of melanin….USE THE SYSTEMIC METFORMIN IN MELASMA.
| Last Update Posted: | August 3, 2021 |
| Last Verified: | August 2021 |
Do antidepressants cause hyperpigmentation?
Conclusions: Psychotropic drugs associated with cutaneous hyperpigmentation include amitriptyline, chlorpromazine, citalopram, desipramine, imipramine, mirtazapine, phenytoin, sertraline, and thioridazine. The hyperpigmentation may initially appear many years after starting the medication.
Can medicines cause skin problems?
Drug rashes, or drug eruptions, are reactions your skin may develop in response to certain drugs. While any drug can cause a rash, certain types are more notorious for causing reactions.
What drugs cause skin problems?
Methamphetamine and the Skin This is called parasitosis, or “meth mites.” They may also suffer from dry skin and skin infections. Users who inject methamphetamine, as well as cocaine, heroin, or any injectable drug, are at great risk for skin infections.
Which is the best cream for chloasma treatment?
The best creams for chloasma contain hydroquinone. This ingredient is effective because it impacts the formation, melanization and degradation of melanosomes. It is the “gold standard” for melasma treatment due to its depigmenting capabilities.
Are there any medications that can cause leg swelling?
Gabapentin is known to cause lower leg swelling. In studies on patients with shingles, swelling appeared in 8% of the patients taking gabapentin. Pregabalin (Lyrica) may also cause swelling in the feet and legs.
Are there any medications that can cause melasma?
Other possible causes of melasma include: Antiseizure medications: Drugs that prevent you from having seizures may be a cause of melasma. An example of an antiseizure medication is Clobazam (Onfi®).
Which is the best way to prevent chloasma?
Sun protection is the best means to avoid developing the condition in the first place. Although sunscreen will help some, it is best to take sun protection further if you have other risk factors for chloasma, such as family history or a dark complexion. When you spend time in the sun, be sure to wear a wide-brimmed hat and sunglasses.