What is sublingual GTN?
GTN sublingual tablets are designed to dissolve quickly under the tongue. This area of the mouth has a large supply of blood vessels that allows the medicine to be rapidly absorbed. Glyceryl trinitrate taken in this way is used to give rapid relief from the pain of an angina attack.
How do you take sublingual GTN?
How to take GTN tablets
- Sit down.
- Put a tablet under your tongue and close your mouth.
- Allow the tablet to dissolve slowly – do not suck, chew or swallow it.
- Close the container – this is important, so your tablets do not lose their strength.
- Rest for a while, then stand up slowly.
What is the GTN protocol?
GTN works in two ways. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body….About glyceryl trinitrate for angina.
| Type of medicine | A nitrate |
|---|---|
| Used for | Chest pain associated with angina |
What is the mechanism of action of GTN?
Glyceryl Trinitrate is a vasodilating agent. Its principle pharmacological action is the relaxation of vascular smooth muscle. Glycerol Trinitrate produces, in a dose related manner, dilation of both arterial and venous beds.
Why GTN is given sublingually?
Nitrates. Glyceryl trinitrate (or nitroglycerin) undergoes extensive hepatic presystemic metabolism when given orally, and is therefore usually given by the sublingual route, by which it is well absorbed and rapidly taken up into the circulation.
Why must GTN be given sublingually?
♥ Glyceryl trinitrate works to relax your blood vessels, allowing more blood and oxygen to reach your heart. ♥ It is given under the tongue so it can work quickly to reduce angina symptoms.
How do you dilute GTN?
Glyceryl Trinitrate need not be diluted before use but can be diluted by 1:10 up to 1:40 with 5 % glucose solution, 5 % glucose solution and 0.9 % sodium chloride solution, or with 0.9 % sodium chloride solution. The solution, whether or not diluted, should be infused slowly and not given by bolus injection.
What schedule is GTN?
In making my decision, among other things, I relied on evidence that there is a lack of safer alternatives and that GTN has a long history in the market place as a Schedule 3 medicine.
What is IV GTN used for?
An infusion of glyceryl trinitrate (GTN) is one of the key components in the treatment of acute left ventricular failure (LVF). Patients can be extremely unwell and are therefore often managed in the emergency department resuscitation room, a place where it is not unusual for larger intravenous cannulae to be sited.
Why is nitroglycerin given sublingually?
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.
Why must glyceryl trinitrate be administered sublingually?