Can nimodipine be given IV?
Be aware that nimodipine should be administered ONLY by the oral route or via nasogastric tube. It should NEVER be administered intravenously.
What is nimotop for?
Nimotop tablets contains nimodipine, which belongs to a group of medicines called calcium antagonists. Nimotop tablets are used to prevent changes in brain function after bleeding around the brain (subarachnoid haemorrhage).
How do you administer nimodipine?
Nimotop (nimodipine) is given orally in the form of ivory colored, soft gelatin 30 mg capsules for subarachnoid hemorrhage. The oral dose is 60 mg (two 30 mg capsules) every 4 hours for 21 consecutive days, preferably not less than one hour before or two hours after meals.
Does nimotop lower heart rate?
Careful observation of blood pressure and heart rate in patients with subarachnoid hemorrhage during therapy with nimodipine showed that blood pressure decreases mainly in hypertensive patients during the first hours of therapy or when treatment is started immediately with 2 mg per hour instead of the recommended …
Is nifedipine the same as nimodipine?
Nimodipine (Dihydro-piridine group) is one more anti-hypertensive drug with similar mechanism of action as Nifedipine and lowers the blood pressure more gradually, hence overcomes the known side effects of Nifedipine and also helps to increase cerebral perfusion pressure4.
Is nimodipine the same as amlodipine?
Nymalize (nimodipine) Lowers blood pressure. Norvasc (Amlodipine) works well to lower blood pressure and prevent chest pain. You can’t miss doses, and you might get persistent swelling.
How does nimotop work?
Nimodipine is thought to work by relaxing narrowed blood vessels in the brain near the area of bleeding so blood can flow more easily. This effect reduces brain damage.
When should nimodipine be given?
It is usually taken every 4 hours for 21 days in a row. Treatment with nimodipine should be started as soon as possible, no later than 96 hours after a subarachnoid hemorrhage occurs.
Why is nimodipine used for SAH?
Nimodipine is used to decrease problems due to a certain type of bleeding in the brain (subarachnoid hemorrhage-SAH). Nimodipine is called a calcium channel blocker. The body naturally responds to bleeding by narrowing the blood vessel to slow blood flow.
What are the side effects of nimodipine?
Side Effects
- Blurred vision.
- chest pain or discomfort.
- difficult or labored breathing.
- fast, pounding, or irregular heartbeat or pulse.
- lightheadedness, dizziness, or fainting.
- shortness of breath.
- slow or irregular heartbeat.
- swelling.
How does nimodipine prevent vasospasm?
Nimodipine is a dihydropyridine that blocks calcium influx through the L-type calcium channels. It is the most rigorously studied and only drug approved by the US Food and Drug Administration for use in treatment of vasospasm.
Why is amlodipine banned in Canada?
The affected medication may contain traces of N-nitrosodimethylamine (NDMA), a “probable human carcinogen” that could increase the risk of cancer through long-term exposure above acceptable levels, Health Canada says.
How many mg of nimodipine is in a Nimotop capsule?
Nimotop capsules are formulated as soft gelatin capsules for oral administration. Each liquid filled capsule contains 30 mg of nimodipine in a vehicle of glycerin, peppermint oil, purified water and polyethylene glycol 400.
What happens if you take Nimotop on IV?
The drug is available in a soft gelatin capsule and is normally given orally. However, the inadvertent intravenous (IV) administration of Nimotop has lead to serious patient harm and death.
How often should you take Nimotop for hemorrhage?
Nimotop is given orally in the form of ivory colored, soft gelatin 30 mg capsules for subarachnoid hemorrhage. Unless otherwise prescribed, the oral dose is 60 mg (two 30 mg capsules) every 4 hours for 21 consecutive days. In general, the capsules should be swallowed whole with a little liquid,…
Is there a generic version of Nimotop in the US?
The Nimotop brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.