How safe is indomethacin?
Indomethacin can increase your risk of fatal heart attack or stroke, even if you don’t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal.
Does indomethacin have side effects?
Upset stomach, heartburn, headache, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What are the long term effects of taking indomethacin?
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs may increase your risk of heart attack, heart failure, or stroke. This risk may be higher if you’re taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure.
How long does indomethacin Extended Release stay in your system?
The mean half-life of indomethacin is estimated to be about 4.5 hours. With a typical therapeutic regimen of 25 or 50 mg t.i.d., the steady state plasma concentrations of indomethacin are an average 1.4 times those following the first dose.
What is indomethacin ER 75 mg used for?
Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, bursitis, and tendonitis. Reducing these symptoms helps you do more of your normal daily activities. The sustained release capsule does not relieve pain quickly. Therefore, do not use it for sudden gout attacks.
How long can you safely take indomethacin?
Indomethacin capsules, USP 75-150 mg daily in 3 or 4 divided doses. The drug should be discontinued after the signs and symptoms of inflammation have been controlled for several days. The usual course of therapy is 7-14 days.
Does indomethacin cause anxiety?
Results: Thirty-two patients experienced a psychiatric reaction after receiving indomethacin for postpartum pain. The symptoms were often severe and included dizziness, anxiety, fear, agitation, affective lability, depersonalization, paranoia, and hallucinations.
How long can you take indomethacin?
Adults—75 to 150 milligrams (mg) per day, divided into three or four equal doses, and taken for 1 to 2 weeks as determined by your doctor.
Will indomethacin raise blood pressure?
The most widely studied of the NSAID medications is indomethacin, which has been shown to increase mean blood pressure by as much as 5 mm Hg in treated hypertensive patients….Table 3.
| Treatment | Losartan |
|---|---|
| Daytime Diastolic BP, mm Hg | 97.5±0.6 |
| Nighttime Systolic BP, mm Hg | 138.5±1.3 |
| Nighttime Diastolic BP, mm Hg | 83.8±0.8 |
Is indomethacin a strong drug?
Indomethacin is one of the most potent NSAIDs and is generally only used after other NSAIDs have proved ineffective. NSAIDs (including indomethacin) have been associated with an increased risk of stroke or heart attack.
Does indomethacin raise blood pressure?
The most widely studied of the NSAID medications is indomethacin, which has been shown to increase mean blood pressure by as much as 5 mm Hg in treated hypertensive patients.
Can indomethacin make you feel weird?
Common side effects may include: indigestion, nausea; headache; or. dizziness.
Does indomethacin Make you Sleepy?
yes,More common Indomethacin side effects may include abdominal pain, constipation, depression, diarrhea, dizziness, fatigue, headache,nausea, ringing in the ears, sleepiness or excessive drowsiness, stomach pain, stomach upset, vertigo , and vomiting..
Is Indomethacin safe?
Indomethacin can increase your risk of fatal heart attack or stroke, even if you don’t have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG ). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal.
What is Indomethacin used for?
Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. Indomethacin is also used to treat shoulder pain caused by bursitis or tendinitis.