What is the difference between Clexane and fraxiparine?

What is the difference between Clexane and fraxiparine?

Clexane® has a molecular weight range from 3000 to 10000 (mean 5000) daltons. Fraxiparines is produced by depolymerisation and ethanol precipitation of commercially available heparin. It has a molecular weight range form 2000 to 8000 (mean 4500) daltons.

Is fraxiparine the same as heparin?

Fraxiparine (nadroparin calcium), a low molecular weight heparin, is a heterogeneous combination of sulphated polysaccharide glycosaminoglycan chains. It is used to treat deep vein thrombosis in the clinic.

What is the difference between Clexane and heparin?

LMWH, such as enoxaparin, is made from heparin. It is also available as a liquid injectable solution used to prevent blood clots, but it is used differently than heparin. LMWH produces a more predictable anticoagulant response so frequent monitoring is not needed to adjust the dose.

What is the difference between Fragmin and Clexane?

Clexane was chosen because it was slightly cheaper than Fragmin. Experts in haematology stated that a daily dose of 40 mg Clexane was equivalent to 5,000 units of Fragmin in high risk surgery.

How do you give a fraxiparine injection?

Method for subcutaneous administration:

1. A suitable site for injection is the skin on the lower part of the stomach, away from any wound or joints.
2. Pinch a skin fold.
3. Maintain the fold and insert the needle vertically to its full depth then inject Fraxiparine over 10 to 15 seconds.

What is fraxiparine used for?

Fraxiparine is used to prevent the blood from clotting after having surgery, during haemodialysis, during hospitalisation for acute illness or in intensive care unit with extended bed rest and is also used to treat existing blood clots that are blocking blood vessels.

Is fraxiparine an anticoagulant?

However Fraxiparine has a longer-lasting anticoagulant activity than Calciparine. These results are in good agreement with clinical observations in man, and thus in favour of our model of human venous thrombogenesis for further studies of antithrombotic molecules.

Is Clexane better than heparin?

Conclusions: This study suggests that a single-dose protocol of Clexane is an effective and very convenient alternative to sodium heparin, but currently direct costs are about 16% more. We recommend an initial dose of 0.70 mg/kg.

What is the difference between UFH and LMWH?

Compared with UFH, the LMWH enoxaparin binds less avidly to plasma proteins, and therefore has increased bioavailability and duration of action. When coupled with antithrombin III, enoxaparin has weaker activity against thrombin, but unlike UFH, it has more potent inhibition of factor Xa.

Is the Fragmin the same as enoxaparin?

Are Fragmin and Lovenox the Same Thing? Lovenox (enoxaparin sodium) Injection and Fragmin (dalteparin) are blood thinners (anticoagulants) used to prevent blood clots that are sometimes called deep vein thrombosis (DVT), which can lead to blood clots in the lungs.