What is povidone K30 used for?
It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems. Povidone k30 has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder.
Is PVP K30 toxic?
PVP is found to be non-toxic, non-irritant, non-sensitizer, and hence completely safe for use in animals and humans for both foods, medical and pharmaceutical applications.
What type of polymer is PVP?
PVP or povidone is a hygroscopic, amorphous, synthetic polymer consisting of linear 1-vinyl-2-pyrrolidinone groups.
What is K value PVP?
The K value of PVP is actually the characteristic value related to the relative viscosity of PVP aqueous solution, and the viscosity is the physical quantity related to the molecular weight of polymer, so the K value can be used to characterize the average molecular weight of PVP.
Is PVP safe to eat?
The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe.
Is PVP chemical toxic?
PVP (Polyvinylpyrolidone) (9003-39-8) Non-toxic in contact with skin (LD50 skin> 5000 mg/kg). Not irritant to skin. Not irritant to respiratory organs.
How do you crosslink in PVP?
Crosslinking of PVP with persulfate involves abstraction of a hydrogen atom from the polymer chain by an SO4- or OH radical. The macroradical thus formed moves by virtue of molecular or segmental diffusion to another macro- radical and forms a stable covalent crosslink.
What kind of polymer is PvP K 30?
PVP (Polyvinylpyrrolidone) K-30 polymer is a hygroscopic, amorphous polymer. They are linear nonionic polymers that are soluble in water and organic solvents and are pH stable. PVP K-30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties.
How is PvP K30 used in contact lenses?
Used in contact lenses to increase their hydrophilicity and lubricity. PVP K30 has been officially listed with the approval of the National Pharmaceutical Administration. The company also supplies Povidone K30 with approval number.
What are the properties of PvP in water?
They are linear nonionic polymers that are soluble in water and organic solvents and are pH stable. PVP K-30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. Key Attributes. Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers.
What makes Polyvinylpyrrolidone a water soluble polymer?
Polyvinylpyrrolidone (PVP), also commercially known as K30, is a water soluble polymer. It has a hygroscopic nature with good adhesive properties. It has a stable pH and has the ability to form transparent films.