What is zuclopenthixol decanoate used for?
Zuclopenthixol is a psychiatric medication (antipsychotic-type) that works by helping to restore the balance of certain natural substances in the brain (neurotransmitters). This medication can improve the symptoms of schizophrenia, making it easier to function in everyday life.
Is Clopixol the same as zuclopenthixol?
Clopixol Injection contains the active substance zuclopenthixol. It belongs to a group of medicines known as antipsychotics (also called neuroleptics).
What type of drug is zuclopenthixol?
Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors. Zuclopenthixol also has high affinity for alpha1-adrenergic and 5-HT2 receptors.
What is zuclopenthixol made of?
Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound belongs to the thioxanthenes. These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom.
What is Zuclopenthixol acetate?
Zuclopenthixol Acetate (Clopixol Acuphase®) is a parenteral antipsychotic which can be prescribed for “the initial treatment of acute psychoses including mania and exacerbation of chronic psychoses, particularly where a rapid onset of action and duration of effect of 2-3 days is desirable”.
How does Zuclopenthixol decanoate work?
Zuclopenthixol works by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is a natural compound called a neurotransmitter, and is involved in transmitting messages between brain cells.
What are the main side effects of Zuclopenthixol acetate?
Dizziness, lightheadedness, drowsiness, constipation, headache, dry mouth, blurred vision, difficulty urinating, tiredness, or pain/redness at the injection site may occur. If these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling.
What is Flupentixol used for?
Flupentixol is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain. Long-acting, or ‘depot’, injections are used once your symptoms have been eased by taking tablets.
What is zuclopenthixol acetate?
How quickly does zuclopenthixol work?
It may take 1 to 2 weeks to notice an effect from this drug and up to 4 weeks to experience the full effect. For severe agitation or other symptoms, use a short-acting medication as directed by your doctor.
How quickly does Zuclopenthixol work?
Where is the decanoate ester found in zuclopenthixol?
Upon reaching the body water phase, the decanoate ester is slowly released from the oil depot, which is resultantly hydrolyzed to the active substance, zuclopenthixol. The decanoate ester provides a means of slow release since zuclopenthixol itself is a short-acting drug. Primarily in the feces with approximately 10% in the urine.
Are there any side effects to taking zuclopenthixol acetate?
Side effect data were poorly reported but there is no evidence of a consistent difference between zuclopenthixol acetate and other ‘standard drugs’ for either the pattern of side effects or the wish to leave the study early.
Which is the best formulation of zuclopenthixol to take?
The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance. Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent.
How long does it take for zuclopentixol acetate to go down?
Most available long-acting depots (excluding zuclopentixol acetate) share similar kinetic properties. Most achieve maximal plasma levels gradually over approximately 4–7 days followed by a gentle decline in the subsequent few weeks.