Can moxidectin be used on horses?

Can moxidectin be used on horses?

Moxidectin has been demonstrated to be safe for most horses, including breeding mares, stallions and even young foals, when administered at up to 3 times the recommended dose of 0.4 mg/kg bwt (Rulli 1996). When the concentration of moxidectin in the serum is high, moxidectin is able to cross the blood-brain barrier.

What is moxidectin for horses?

Moxidectin is a second generation macrocyclic lactone (ML) with potent endectocide activity. It is used for parasite control in horses in an oral gel formulation. The principal mode of action of MOX and of other MLs is binding to gamma-aminobutyric (GABA) and glutamate-gated chloride channels.

Is ivermectin the same as moxidectin?

Moxidectin, a macrocyclic lactone like ivermectin, is approved and marketed worldwide as a treatment for internal and external parasites in wide variety of companion and farm animals.

What Horse Wormer has moxidectin?

Equest Horse Wormer
Equest Horse Wormer (Moxidectin) Treats 700kg.

What is moxidectin used for in animals?

Moxidectin topical (brand names: Advantage Multi®, Advocate®, ProHeart®) is a topical avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites (hookworms, roundworms, and whipworms), and is combined with imidacloprid to also treat fleas.

Who makes moxidectin?

History. In the late 1980s, an American Cyanamid Company agronomist discovered the Streptomyces bacteria from which moxidectin is derived in a soil sample from Australia. Two companies filed patents for moxidectin: Glaxo Group and the American Cyanamid Company; in 1988, all patents were transferred to American Cyanamid …

How long does it take moxidectin to work?

Moxidectin will start working in about 24 hours to kill ticks and intestinal parasites. Imidacloprid, the medication paired with topical moxidectin, begins to kill fleas within 4 hours.

What are the ingredients in moxidectin?

Each tablet contains 2 mg of moxidectin. The tablets are uncoated and include the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, lactose anhydrous, magnesium stearate, microcrystalline cellulose and sodium lauryl sulfate.

What is the most effective horse wormer?

The 8 Best Horse Wormer – Reviews 2020

1. Panacur Equine Paste Horse Dewormer – Best Overall.
2. Farnam Ivercare Horse Dewormer – Best Value.
3. Bimeda Equimax Horse Wormer – Premium Choice.
4. Durvet Ivermectin Paste Dewormer.
5. Merial Zimecterin Gold Dewormer.
6. Durvet Duramectin Equine Wormer.
7. Intervet Safeguard Horse Dewormer.

Is moxidectin safe for goats?

Moxidectin (Cydectin) is not approved for use in goats; therefore, there are no established withdrawal times (WDT) for meat and milk.

Is moxidectin FDA approved?

The United States Food and Drug Administration (FDA) has approved moxidectin as the first new treatment for river blindness in 20 years, adding new ammunition to the fight to eliminate this disabling disease.

Can you overdose on moxidectin?

An overdose of moxidectin enhances the effect of gamma-aminobutyric acid (GABA) in the central nervous system. In horses, overdose may lead to depression, drooping of the lower lip, tremor, lack of coordination when moving (ataxia), decreased rate of breathing (respiratory rate), stupor and coma.

How much moxidectin do you give a horse?

INDICATIONS. QUEST PLUS Gel (moxidectin/praziquantel) when administered at the recommended dose level of 0.4 mg moxidectin/kg and 2.5 mg praziquantel/kg (2.2 lb) body weight is effective in the treatment and control of the following stages of gastrointestinal parasites in horses and ponies:

What kind of Worms does quest equine gel treat?

Quest Equine Gel Horse Wormer (Moxidectin)is specially formulated palatable dewormer gel for horses and ponies. The new drug Moxidectin is distinctly different from other paste wormers. Effective in the treatment of large and small strongyles, encysted cyathostomes, ascarids, pin worms, hair worms, large mouth stomach worms and bots.

Why do you put Quest Gel in your horses mouth?

Gel melts in the horses mouth to prevent waste. Quest Gel is used to aid in the control of: hairworms stomach worms bots encysted small strongyles Treats up to 1500 lb. View manufacturer and/or label information Brief content visible, double tap to read full content.