Can superficial bladder cancer spread?
Superficial bladder cancer means it started in the lining of the bladder and hasn’t spread beyond it. Another name for it is non-muscle-invasive bladder cancer.
Can superficial bladder cancer become invasive?
These results demonstrate that superficial, low grade transitional cell carcinoma of the bladder can become muscle invasive despite careful surveillance and a long dormant period.
Is it common for bladder cancer to recur?
Low-grade bladder cancers recur frequently, and recurrences require treatment with a procedure called transurethral resection for bladder tumor, or TURBT. Some patients experience multiple recurrences and, as a result, undergo repeated surgeries.
What causes superficial bladder cancer?
Currently, cigarette smoking is by far the most common cause of bladder cancer, although occupational exposure to arylamines has been implicated in the past. Gross or microscopic hematuria is the most common sign at presentation.
What is a superficial bladder Tumour?
Superficial bladder cancer is also called non-muscle invasive bladder cancer. This type of bladder cancer is found on the surface of the inside lining of the bladder. It is the most common type of bladder cancer, and is found in about 75% of new patients with bladder cancer.
What are the odds of bladder cancer returning?
Nearly three-fourths of patients diagnosed with high-risk bladder cancer will recur, progress, or die within ten years of their diagnosis.
How do you know if bladder cancer has returned?
Tell your doctor about any new symptoms, such as pain during urination, blood in the urine, frequent urination, an immediate need to urinate, and any other symptoms. These symptoms may be signs that the cancer has come back or signs of another medical condition.
What is a superficial TCC?
Superficial transitional cell carcinomas (TCC) of the urinary bladder, defined as those that are restricted to the mucosa or the lamina propria, represent a common condition with a wide spectrum of biologic significance.
Does size of bladder tumor matter?
CONCLUSIONS: Larger tumor size (>5 cm) is associated with greater length of stay, reoperation, readmission, and death following TURBT. Patients should be counseled appropriately and likely warrant vigilant observation prior to and following hospital discharge.
What is superficial TCC?
How do I know if my bladder cancer has returned?
How often does bladder cancer recur?
Why is superficial bladder cancer a nuisance disease?
Superficial bladder cancer can be a frustrating disease for both the patient and physician. It has been referred to as a “nuisance disease” because of its propensity for recurrence, necessitating frequent cystoscopies and trips to the operating room for resection of recurrent disease.
How often to give BCG for superficial bladder cancer?
Patients receiving an antiplatelet oranticoagulant may not respond as well to BCG therapy. I treat patients initially with 50 mg of BCG (Tice) once a weekfor 6 weeks and prescribe another 6 week cycle if the 3-monthcystoscopy shows evidence of recurrence.
Which is the most effective carcinoma treatment for bladder cancer?
There are ample data, much of which is cited in the article, tosuggest that BCG lowers tumor recurrence and progression ratesand is likely the most effective agent for treating carcinomain situ. The mechanism of action of BCG is not clear but seemsto be T-cell-mediated; the drug requires fibronectin binding inthe bladder for efficacy.
Can a tumor be implanted on the bladder wall?
Tomy mind, the best evidence supporting its occurrence comes fromstudies in experimental animals showing that a suspension of tumorcells will implant on a scarified bladder wall as a reproduciblemodel. [4] The data cited in the manuscript support the notionthat tumor implantation does occur and that perioperative treatmentmay prevent it.