What is urothelial papillary carcinoma?
Papillary urothelial carcinoma is a type of bladder cancer. It starts in urothelial cells in the bladder lining. Urothelial cells also line the urethra, ureters, and other parts of the urinary tract. Cancer can start in these areas, too.
What does urothelial carcinoma mean in medical terms?
Urothelial carcinoma, also known as transitional cell carcinoma (TCC), is by far the most common type of bladder cancer. In fact, if you have bladder cancer it’s almost certain to be a urothelial carcinoma. These cancers start in the urothelial cells that line the inside of the bladder.
What does invasive papillary urothelial carcinoma mean?
Most papillary urothelial carcinomas are non-invasive which means the cancer cells are only seen in the epithelium. A tumour is called invasive if the cancer cells have spread beyond the epithelium into the lamina propria below.
What is urothelial carcinoma of the prostate?
Primary urothelial carcinoma of the prostate is a rare solid malignant tumor that exhibits highly aggressive biological behavior and has a poor prognosis.
What is papillary urothelial?
Papillary urothelial carcinoma is a form of bladder cancer. It develops within a type of cell in the inner lining of the bladder, ureters, and lower kidneys. The bladder is a muscular organ in the pelvis that stores urine. Bladder cancer develops when abnormal cells in the bladder grow too quickly.
What papillary means?
: of, relating to, being, or resembling a papilla or nipple-shaped projection, mass, or structure : marked by the presence of papillae papillary thyroid carcinoma tumors with papillary projections.
How aggressive is urothelial carcinoma?
Muscle-invasive urothelial carcinomas are highly aggressive compared to cancers of the upper urinary tract, carrying a five-year disease-specific survival rate of <50% in pT2/pT3 disease, and this survival rate drops below 10% in pT4 cancer.
How is urothelial carcinoma diagnosed?
Urine cytology is the most widely used noninvasive test to detect urothelial tumors. However, it is limited by its low sensitivity. On the other hand, cystoscopy is the gold standard procedure to follow patients with a history of bladder cancer but this test is invasive and costly.
Are papillary tumors cancerous?
Papillary tumors may be benign (not cancer) or malignant (cancer). Papillary tumors occur most often in the bladder, thyroid, and breast, but they may occur in other parts of the body as well.
What is invasive urothelial carcinoma?
Invasive urothelial carcinoma is a type of transitional cell carcinoma. It is a type of cancer that develops in the urinary system: the kidney, urinary bladder, and accessory organs.
What is a urothelial cell?
(YOOR-oh-THEE-lee-ul KAN-ser) Cancer that begins in cells called urothelial cells that line the urethra, bladder, ureters, renal pelvis, and some other organs. Urothelial cells are also called transitional cells. These cells can change shape and stretch without breaking apart. Also called transitional cell cancer.
Where is urothelium found?
The urothelium is exclusively in urinary structures such as the ureter, urinary bladder, and proximal urethra. The urothelium is composed of three layers[3][4]: Apical layer – The innermost layer serves as a barrier between the bladder lumen and the underlying tissue.
What is renal papillary?
The renal papilla is the location where the renal pyramids in the medulla empty urine into the minor calyx in the kidney. Histologically it is marked by medullary collecting ducts converging to form a papillary duct to channel the fluid. Transitional epithelium begins to be seen.
What is the treatment for papillary cancer?
Therapeutic options include: Surgery: The most common treatment for papillary carcinoma is surgical removal of the breast (mastectomy). This approach helps reduce the chances of the cancer recurring. Hormone therapy: Rarely, hormone therapy may be recommended for women with papillary carcinoma.
What is the prognosis for papillary thyroid cancer?
The survival rate for papillary thyroid cancer is exceptional. More than 95% of adults with this cancer survive a minimum of 10 years. The prognosis is better for people who are below 40 and for those with smaller sized tumors.
What is the prognosis for high grade bladder cancer?
Patients with T1 high-grade (T1HG) bladder cancer have a 10-year recurrence rate of ~77%, a 10-year progression rate of ~42% and a 10-year cancer-specific mortality of ~15%.
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