What is the chromosome 3p25 26?
This suggests that 3p25-26 is a new locus for severe recurrent depression. This represents the first report of a genome-wide significant locus for depression that also has an independent genome-wide significant replication.
What chromosome is linked to depression?
RESEARCHERS HAVE IDENTIFIED A DNA REGION ON CHROMOSOME 3 THAT APPEARS TO BE RELATED TO DEPRESSION. THE DISCOVERY WAS MADE INDEPENDENTLY BY GROUPS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS AND AT KING’S COLLEGE LONDON.
How do genetics play a role in depression?
However, research into the genetics of depression is in its early stages, and very little is known for certain about the genetic basis of the disease. Studies suggest that variations in many genes, each with a small effect, combine to increase the risk of developing depression.
What gene causes depression?
The depression gene The chromosome 3p25-26 was found in more than 800 families with recurrent depression. Scientists believe that as many as 40 percent of those with depression can trace it to a genetic link. Environmental and other factors may make up the other 60 percent.
Is depression due to a chemical imbalance?
It’s often said that depression results from a chemical imbalance, but that figure of speech doesn’t capture how complex the disease is. Research suggests that depression doesn’t spring from simply having too much or too little of certain brain chemicals.
Is there a genetic marker for depression?
Whole-exome sequencing found genetic marker for age at onset (AAO) in depression. Variants in the CCL14, FYB, GPRASP1 and CTNND2 genes were related to earlier AAO. These markers can help early identification of patients at risk of depression.
Are you born with depression or does it develop?
This could mean that in most cases of depression, around 50% of the cause is genetic, and around 50% is unrelated to genes (psychological or physical factors). Or it could mean that in some cases, the tendency to become depressed is almost completely genetic, and in other cases it is not really genetic at all.
What triggers genetic depression?
Many researchers believe there’s no single gene that puts someone at risk for depression. It’s more likely a combination of genes that lead to the disorder. The causes of bipolar disorder and anxiety disorders may also be traced to a combination of genetic factors.