What is leukemia lymphoma evaluation?

B-cell leukemia/lymphoma panel is a blood test that looks for certain proteins on the surface of white blood cells called B-lymphocytes. The proteins are markers that may help diagnose leukemia or lymphoma.

What does leukemia lymphoma panel by flow mean?

Leukemia and lymphoma analysis by flow cytometry aids in identifying the tumor lineage, which in most cases is identified as T cell, B cell, or myeloid. Lineage identification can provide a confirmatory diagnosis or differential diagnosis, prognosis, and treatment options.

What do my flow cytometry results mean?

Flow cytometry can identify the type of cells in a blood or bone marrow sample, including the types of cancer cells. It detects types of cancer cells based on either the presence or the absence of certain protein markers (antigens) on a cell’s surface.

What is Immunophenotyping leukemia lymphoma?

Immunophenotyping is a test used to identify cells on the basis of the types of markers or antigens present on the cell’s surface, nucleus, or cytoplasm. This technique helps identify the lineage of cells using antibodies that detect markers or antigens on the cells, hence the “immuno-” prefix.

What are lymphoma markers?

The most important serological markers reflect the tumor load (beta-2 microglobulin, beta 2-M), proliferative activity (lactic dehydrogenase, LDH), and invasive potential of lymphomas (CA 125). LDH and beta 2-M are included as important prognostic parameters in widely used staging systems.

What are markers in blood work for leukemia?

How Is Leukemia Treated? Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.

Is flow cytometry accurate?

The diagnostic accuracy of FC was 88.4%, sensitivity was 85.8%, and specificity was 92.9%. In addition, FC accuracy for classes of non-Hodgkin lymphoma was assessed. We conclude that FC is an independently accurate ancillary test in the evaluation of FNA.

What lab values indicate leukemia?

What is a normal flow cytometry?

Flow cytometry is a laboratory method used to detect, identify, and count specific cells. This method can also identify particular components within cells. This method may be used to evaluate cells from blood, bone marrow, body fluids such as cerebrospinal fluid (CSF), or tumors.

What do you mean by cytometer?

Cytometry is the measurement of the characteristics of cells. In a similar fashion, cytometry is also used in cell biology research and in medical diagnostics to characterize cells in a wide range of applications associated with diseases such as cancer and AIDS.

Why do we do immunophenotyping?

Flow cytometry immunophenotyping is used primarily to help diagnose and classify blood cell cancers (leukemias and lymphomas) and to help guide their treatment.

What are leukemia markers?

Leukemia Markers Leukemia or leukaemia is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes).

What is blood test for leukemia?

A complete blood count (CBC) test is the first level of diagnostic testing for leukemia. For this test, a lab will analyze a sample blood and count the white blood cells, red blood cells, and platelets . A sample with a high level of white blood cells and low levels of red blood cells can indicate leukemia.

What is the diagnosis for leukemia?

Diagnosing leukemia usually begins with a medical history, physical examination and blood test. During the physical exam, your doctor may check for signs of pale skin, bruising, swollen lymph nodes or an enlarged spleen. A complete blood count ( CBC ) is one of several common tests for leukemia.

What is a Leukemia Lymphoma panel?