What is the best timing for IUI after hCG shot?

What is the best timing for IUI after hCG shot?

The current practice in intrauterine insemination (IUI) cycles is to perform the IUI 24-36 hours after the hCG administration, when the ovulation is already imminent.

What day of ovulation is best for IUI?

IUI should be done on the day of ovulation, which occurs the day following a positive result with a commercial ovulation predictor kit, or 36-40 hours after an HCG trigger shot.

Can you do IUI 24 hours after trigger?

IUI performed at either 24 hours or 36 hours after ovulation triggered by hCG injection does not change clinical pregnancy rates for PCOS patients. Patients with unexplained infertility seem to benefit from earlier IUI procedures, which increases their fertility potential during ovulation induction with gonadotropins.

How long after ovidrel does the egg release?

The patient will receive just one injection of a hormone called human chorionic gonadotropin (Ovidrel) that will cause the egg(s) to be released about 38-40 hours later and to mature the egg(s) for fertilization. 36 hours after the Ovidrel injection, she is ready for the intrauterine insemination.

How many hours before IUI should you trigger?

IUI is generally performed 34–36 h after hCG trigger in cycles augmented with the ovarian stimulation (10), and this is done while keeping in mind that the oocyte remains fertilizable for a brief period of time (12–16) hours after ovulation (4).

How long does ovidrel 250 mcg stay in your system?

Following subcutaneous administration of Ovidrel®, hCG is eliminated from the body with a mean terminal half-life of about 29 ± 6 hours. After intravenous administration of Ovidrel® 250 µg to healthy down-regulated females, the mean terminal half-life is 26.5 ± 2.5 hours and the total body clearance is 0.29 ± 0.04 L/h.

How many hours before IUI do you trigger?

What does trigger shot do IUI?

What does the trigger shot do? Whereas other gonadotropins — like follicle-stimulating hormone (FSH) and LH — work on both growing and maturing the eggs, a trigger shot of hCG helps the ovaries release those mature eggs as part of ovulation.

Can you ovulate earlier than 36 hours after trigger shot?

After receiving an injection of human chorionic gonadotropin, ovulation can occur between 24-48 hours, with the average time being within 36 hours. Ovulating as early as 24 hours is less likely, however, it can happen and couples should be prepared.

Why is IUI scheduled 36 hours after trigger?

The IUI is scheduled 36 hours after the trigger medication is injected. Awaiting Natural Ovulation: Blood work or urine-based ovulation predictor kits (OPKs) can predict when a woman will naturally ovulate. In this case, the IUI occurs either later that day or the next morning.

Can follicles still grow after trigger shot?

If the follicle does not reach 18-20 mms, it is unlikely that the follicle will ovulate despite HCG (Ovidrel). They do continue to grow a little, but the follicle has not reached ovulatory size.

How do I know if trigger shot worked?

After the trigger shot is given, the couple is instructed to have sex daily to every other day for three days in the privacy of their home. Roughly a week following timed intercourse, a blood test will evaluate progesterone levels to confirm the trigger shot caused ovulation.

When do you ovulate after an Ovidrel shot?

Most Drs seem fairly confident that Ovidrel induces ovulation around 36hrs after the shot, mine included. I felt myself ovulate around 38hrs after the trigger and then had the IUI a couple of hours later. That timing worked for me – we got out BFP on IUI #2.

When to start the IUI after ovulation?

Sperm delivery (intercourse or IUI) should occur within the following 36-48 hours. For IVF patients, egg retrieval occurs precisely 35-36 hours after Ovidrel/HCG shot. Progesterone supplementation will start 48 hours after Ovidrel. Pregnancy testing will be scheduled 14 days after your trigger.

What is the success rate of Ovidrel trigger shots?

18.2% for those that received an r-hCG shot. Only 5.8% for cycles with no r-hCG shot. 30.7% for those who received the trigger shot at the same time as their body’s natural LH surge. Most studies do not find a difference in pregnancy success rates when comparing r-hCG (like Ovidrel) and u-hCG (urinary extracted hCG).

Can you use Ovidrel for weight loss outside of fertility treatment?

Ovidrel and other forms of hCG have been used in weight loss protocols, outside of the world of infertility and fertility treatments. There’s little to no evidence, however, that Ovidrel can help you lose weight.