What is a normal insulin sensitivity factor?

According to the ADA, the target level should be as close as possible to the levels that a person without diabetes would have. These are: Between 70–130 mg/dL before a meal. No higher than 180 mg/dL up to 2 hours after a meal..

How do you calculate insulin sensitivity factor?

To calculate your insulin sensitivity factor for regular insulin, use the “1500 rule.” It will help you know how much your blood sugar will drop per unit of regular insulin. For example, if your recommended daily dose of regular insulin is 30 units, divide that into 1500 to get 50.

How is ISF calculated?

The 100 rule (1800 rule for mg/dl) has been used to find the insulin sensitivity factor (ISF), that is, how many mmol/l (or mg/dl) 1 unit of insulin lowers the blood glucose level. ISF equals 100 divided by TDD (1800 divided by TDD for mg/dl).

What is abnormal insulin sensitivity?

Some signs of insulin resistance include: A waistline over 40 inches in men and 35 inches in women. Blood pressure readings of 130/80 or higher. A fasting glucose level over 100 mg/dL. A fasting triglyceride level over 150 mg/dL.

Is it good to be insulin sensitive?

While insulin resistance is harmful to your health, insulin sensitivity is beneficial. Insulin resistance occurs when your cells stop responding to the hormone insulin. This causes higher insulin and blood sugar levels, potentially leading to type 2 diabetes.

What causes insulin sensitivity?

While genetics, aging and ethnicity play roles in developing insulin sensitivity, the driving forces behind insulin resistance include excess body weight, too much belly fat, a lack of exercise, smoking, and even skimping on sleep. As insulin resistance develops, your body fights back by producing more insulin.

How do you calculate mmol insulin sensitivity?

Creating an Insulin Sensitivity Factor

100/TDD = ISF if using rapid insulin (the number of mmol that 1 unit drops glucose in 3-4 hours approx)
83/TDD= ISF is using regular/Toronto insulin (the number of mmol/L that 1 unit drops glucose in 3-5 hours approx)
EXAMPLE ONE: Teddy, TDD 33, takes rapid insulin.

What is the difference between insulin sensitivity and insulin resistance?

Insulin resistance and insulin sensitivity are two sides of the same coin. If you have insulin resistance, you have low insulin sensitivity. Conversely, if you are sensitive to insulin, you have low insulin resistance.

What is a normal free insulin level?

A normal measurement of free insulin is less than 17 mcU/mL. You may have a false-low result if you have a health problem that’s damaging red blood cells. If your levels are higher, it may mean you have been using too much insulin in medicine form.

Do you want high or low insulin sensitivity?

What is the insulin sensitivity Factor ( ISF ) for Teddy?

100/TDD = ISF if using rapid insulin (the number of mmol that 1 unit drops glucose in 3-4 hours approx) 83/TDD= ISF is using regular/Toronto insulin (the number of mmol/L that 1 unit drops glucose in 3-5 hours approx) 1 unit rapid insulin is expected to lower Teddy’s blood sugar by about 3 mmol/L.

What should the insulin sensitivity factor be for Sandy?

Example: 13 mmol/L – 7 mmol/L target / ISF of 2 = 3 units to correct high blood sugar This correction insulin would be given in addition to the meal bolus (insulin to cover the food). E.g. Sandy has high readings using an ISF of 3. The formula suggests an ISF of 1. In this situation consider a new ISF of 2 to start, as it is safer.

How is the insulin sensitivity index ( OGTT ) calculated?

There are two groups of insulin sensitivity indices: (1) Indices calculated by using fasting plasma concentrations of insulin, glucose and triglycerides, (2) indices calculated by using plasma concentrations of insulin and glucose obtained during 120 min of a standard (75 g glucose) OGTT [Tables [Tables11and and22]. Table 1

What does the ISF of 1 mean in diabetes?

For example: ISF of 1 means: 1 unit of bolus insulin lowers glucose by 1 mmol/L ISF of 2 means: 1 unit of bolus insulin lowers glucose by 2 mmol/L ISF of 3 means: 1 unit of bolus insulin lowers glucose by 3 mmol/L