Does Gonal F work for PCOS?
Gonal F is prescribed at lower doses to patients with ovulatory issues, especially if they have PCOS, to lower the risk of ovarian hyperstimulation.
Can IUI be successful with PCOS?
Women who have ovulatory dysfunction, such as polycystic ovary syndrome (PCOS), have the best chances of success with IUI compared to infertility resulting from other causes. PCOS is the most common ovulatory disorder affecting one in 10 women.
Is IUI with ovarian stimulation effective in couples with unexplained subfertility?
Summary answer: IUI-OS is associated with higher chances of ongoing pregnancy compared to expectant management in unexplained subfertile couples, specifically those with poor prognoses of natural conception, i.e. <15% over 6 months or <25% over 1 year.
What IVF protocol is best for PCOS?
In the past 20 years, GnRH agonists have been the “National Guideline” protocol in PCOS, and the majority of IVF/intracytoplasmic sperm injection treatment cycles performed.
How fast do follicles grow on GONAL-F?
As the ovary is stimulated with FSH, some of the follicles will grow. Follicles grow approximately 2 mms per day so there is some predictability of when the follicles will reach the appropriate size for ovulation or retrieval.
How fast does GONAL-F work?
Gonal-f (follitropin alfa) will be fully absorbed by the body about 11 to 20 hours after your dose, but it can take many months for you to start making more sperm. Most people see results from Gonal-f (follitropin alfa) about 6 to 12 months after starting it, but for some it can take as long as 18 months to work.
Does PCOS affect egg quality?
PCOS has been found to impact egg quality, prevent ovulation, contribute to insulin resistance, and heighten the likeliness of developing certain disorders like gestational diabetes. Women with PCOS who are trying to get pregnant often turn to lifestyle modifications, such as diet and exercise, to increase fertility.
Is IUI or IVF better for unexplained infertility?
It also requires just one sperm cell for each egg, allowing for successful fertilization even in the most severe cases of male infertility. Generally speaking, IVF is the most powerful and successful treatment for all forms of infertility, including age-related infertility and unexplained infertility.
Does IUI work for unexplained infertility?
IUI is often considered as the first line of treatment for unexplained infertility, mild endometriosis or mild male factor infertility. IUI can help patients when: A woman has not been able to conceive using ovulation-inducing fertility medication.
Does PCOS affect IVF success?
The large majority of women with PCOS that have not gotten pregnant with other treatments will be able to have success with IVF if they are under 40 years of age and have their IVF performed at a high quality clinic.
Can you use IUI on a medicated PCOS cycle?
IUI will only be effective in PCOS patients if the patient actually ovulates. Adding on IUI to a medicated Clomid or Letrozole cycle provides a slight bump in conception rates and makes sense especially if there is some mild male factor infertility and sperm movement isn’t ideal.
What’s the success rate of an IUI cycle?
A 2015 retrospective study of over 47,500 IUI cycles looked at fresh post-wash total motile sperm count (which can be up to 30% lower than pre-wash counts) and the associated conception rate. Researchers found couples with a post-wash total motile sperm count of at least 9 million had a pregnancy rate for one IUI cycle of 16.9%.
Can you have IUI if you have 4 follicles?
Most women pairing a medicated cycle with IUI will not be allowed to proceed with IUI if they are growing 4 or more follicles. Studies [9] have shown that multi-follicular growth is associated with increased pregnancy rates in IUI with controlled ovarian hyperstimulation (COH).
Which is better for PCOS Clomid or letrozole?
While Letrozole is the preferred medication for PCOS based on a double-blind, randomized study [5] (especially for women with a BMI over 30 kg/m2), some women have better success with Clomid, while others are resistant to both Letrozole and Clomid and require gonadotropin in order to ovulate.