How do you dilute ertapenem?
Shake well to dissolve and immediately withdraw a volume equal to 15 mg/kg of body weight (not to exceed 1 g/day) and dilute in 0.9% Sodium Chloride Injection to a final concentration of 20 mg/mL or less. 3. Complete the infusion within 6 hours of reconstitution.
How do you dilute Invanz?
INVANZ MUST BE RECONSTITUTED AND THEN DILUTED PRIOR TO ADMINISTRATION. 1. Reconstitute the contents of a 1 g vial of INVANZ with 10 mL of one of the following: Water for Injection, 0.9% Sodium Chloride Injection or Bacteriostatic Water for Injection, using a syringe equipped with a 21-gauge or smaller diameter needle.
How do you administer IV ertapenem?
Preparation for intravenous administration: INVANZ must be reconstituted and then diluted prior to administration. Reconstitute the contents of a 1 g vial of INVANZ with 10 mL of water for injection or sodium chloride 9 mg/mL (0.9 %) solution to yield a reconstituted solution of approximately 100 mg/mL.
Can you give ertapenem IV push?
Several antibiotics are Food and Drug Administration-approved for IV push administration, including many beta-lactams. In addition, cefepime, ceftriaxone, ertapenem, gentamicin, and tobramycin have primary literature data to support IV push administration.
How much lidocaine do you reconstitute ertapenem?
ERTAPENEM FOR INJECTION MUST BE RECONSTITUTED PRIOR TO ADMINISTRATION. Reconstitute the contents of a 1 g vial of ertapenem for injection with 3.2 mL of 1% lidocaine HCl injection (without epinephrine). Shake vial thoroughly to form solution. The resultant concentration is approximately 280 mg/mL.
How much lidocaine do you mix with ertapenem?
Ertapenem, reconstituted with 1% lidocaine HCl injection, USP (in saline without epinephrine), is well absorbed following IM administration at the recommended dose of 1 g. The mean bioavailability is approximately 92%.
What happens when you push IV meds too fast?
Too rapid administration of high doses (greater than 500 mg administered over less than 10 minutes) may precipitate hypotension, cardiac arrhythmia and sudden death.
How do you reconstitute IV antibiotics?
All antibiotics should be prepared prior to case, labeled appropriately, and discarded if unused. Reconstitute a 1 g vial and a 2 g vial each with 10 mL of sterile water for injection • Administer each 1 g dose by slow IV push over 3 to 5 minutes. Administer each 2 g dose by slow IV push over 3 to 5 minutes. minutes.
Can ertapenem be mixed with lidocaine?
Ertapenem, reconstituted with 1% lidocaine HCl injection, USP (in saline without epinephrine), is almost completely absorbed following intramuscular (IM) administration at the recommended dose of 1 g. The mean bioavailability is approximately 90%.
How do you mix Invanz for IM injections?
Preparation for intramuscular administration: INVANZ MUST BE RECONSTITUTED PRIOR TO ADMINISTRATION. Reconstitute the contents of a 1 g vial of INVANZ with 3.2 mL of 1.0% lidocaine HCl injection2 (without epinephrine). Shake vial thoroughly to form solution.
Can you mix ertapenem with lidocaine?
How do you administer Invanz injection?
INVANZ MUST BE RECONSTITUTED PRIOR TO ADMINISTRATION. Shake vial thoroughly to form solution. Immediately withdraw a volume equal to 15 mg/kg of body weight (not to exceed 1 g/day) and administer by deep intramuscular injection into a large muscle mass (such as the gluteal muscles or lateral part of the thigh).
What’s the maximum dose of ertapenem for a 13 year old?
Usual Pediatric Dose for Intraabdominal Infection 3 months to 12 years: 15 mg/kg IV or IM twice a day -Maximum dose: 1 g/day 13 years or older: 1 g IV or IM once a day
What is the bioavailability of ertapenem in im?
Ertapenem, reconstituted with 1% lidocaine HCl injection, USP (in saline without epinephrine), is almost completely absorbed following intramuscular (IM) administration at the recommended dose of 1 g. The mean bioavailability is approximately 90%.
How is the infusion of ertapenem Invanz prepared?
Preparation: (IV): Reconstitute 1 gram vial with 10 mL of Water for Injection, 0.9% Sodium Chloride Injection, or Bacteriostatic Water for Injection and then add contents to 50 ml normal saline. Complete the infusion within 6 hours of reconstitution. (IM): Reconstitute 1 gram vial with 3.2 mL of lidocaine 1% injection without epinephrine.
How often should you take ertapenem for community acquired infections?
1 g IV or IM once daily for 5 to 14 days. Guidelines recommend ertapenem for 4 to 7 days for community-acquired infections. 15 mg/kg/dose IV or IM twice daily (Max: 1 g/day) for 5 to 14 days.